Last reviewed · How we verify
NCT05337696: RECONSTRUCT
Circumferential Vertebral Reconstruction of Osteoporotic Compression Fractures Using a Novel Bipedicular Peek Implant
NA trial testing Vertebral Implant PEEK Procedure in Vertebral Compression Fractures in 30 participants. Terminated before completion.
7 March 2025
Quick facts
| Lead sponsor | Icahn School of Medicine at Mount Sinai |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 10 May 2022 |
| Primary completion | 7 March 2025 |
| Estimated completion | 7 March 2025 |
| Sites | 4 locations across United States |
Drugs / interventions tested
- Vertebral Implant PEEK Procedure
- Vertebral Implant PEEK (VIP) implant
Conditions studied
- Vertebral Compression Fractures — all drugs for Vertebral Compression Fractures →
- Osteoporotic Vertebral Compression Fractures — all drugs for Osteoporotic Vertebral Compression Fractures →
Sponsor
Icahn School of Medicine at Mount Sinai
Who can join
50 and older, any sex, with Vertebral Compression Fractures or Osteoporotic Vertebral Compression Fractures. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The RECONSTRUCT study is a multi-center, prospective, single arm, post-market, pilot study to evaluate clinical and radiologic outcome data regarding the use of the Vertebral Implant PEEK (VIP) implant in the treatment of symptomatic, acute (\<8week) vertebral compression fractures who have failed conservative care strategies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05337696
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Vertebral Compression Fractures
Currently open trials in the same condition.
- NCT06670404 — Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures · recruiting
Other Icahn School of Medicine at Mount Sinai trials
Trials by the same sponsor.
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- NCT07487948 — Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05337696 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Icahn School of Medicine at Mount Sinai
- Last refreshed: 8 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05337696.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing