Who is sponsoring NCT05336786?

NCT05336786 is sponsored by Thomas Jefferson University.

What drugs are being tested in NCT05336786?

Interventions in NCT05336786: Perflutren Lipid Microspheres, Ultrasound.

What condition does NCT05336786 study?

NCT05336786 studies Prostate Carcinoma.

Is NCT05336786 still recruiting?

NCT05336786 is currently active, enrolled. Last updated 4 September 2025.

Last reviewed 2025-09-04 · How we verify

NCT05336786

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)

Active, enrolled Phase 3 Last updated 4 September 2025

What this trial tests

Phase 3 trial testing Perflutren Lipid Microspheres in Prostate Carcinoma in 70 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

15 June 2022

Primary endpoint
26 May 2025

26 May 2026

Quick facts

Lead sponsor	Thomas Jefferson University
Phase	Phase 3
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	70
Start date	15 June 2022
Primary completion	26 May 2025
Estimated completion	26 May 2026
Sites	2 locations across Netherlands, United States

Drugs / interventions tested

Perflutren Lipid Microspheres — full drug profile →
Ultrasound

Conditions studied

Prostate Carcinoma — all drugs for Prostate Carcinoma →

Sponsor

Thomas Jefferson University

Who can join

18 and older, male only, with Prostate Carcinoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This phase III trial investigates if perflutren lipid microspheres with ultrasound can be used to diagnose prostate cancer non-invasively. Definity (perflutren lipid microspheres) is an ultrasound contrast agent that is typically used for ultrasound bubble studies that involve the heart. Definity appears on ultrasound images as tiny gas-filled microbubbles. These microbubbles are about the size of a red blood cell and do not stay in a patient's body for more than several minutes, where they are excreted from the lungs and exhaled back into the air when breathing. Definity may enhance ultrasound images of the prostate and help doctors identify prostate cancer on ultrasound images.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Perflutren Lipid Microspheres

Trials testing the same drug.

NCT06797193 — Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension · NA · recruiting
NCT04715958 — SHAPE Neoadjuvant Chemotherapy Response · Phase 2, PHASE3 · recruiting
NCT06171607 — Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses · Phase 1 · recruiting
NCT03300401 — Contrast-Enhanced Ultrasound in Diagnosing Patients With Liver Cancer Undergoing Yttrium-90 Radioembolization · NA · withdrawn
NCT03297112 — Contrast-Enhanced Subharmonic Ultrasound Imaging in Improving Characterization of Adnexal Masses in Patients Undergoing · EARLY_PHASE1 · completed

Other recruiting trials for Prostate Carcinoma

Currently open trials in the same condition.

NCT07218718 — Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy · NA · recruiting
NCT07202247 — Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabol · Phase 2 · recruiting
NCT06957691 — Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Pro · Phase 2 · recruiting
NCT07291414 — A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients · NA · recruiting
NCT07285044 — The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Tr · Phase 2 · recruiting

Other Thomas Jefferson University trials

Trials by the same sponsor.

NCT07526480 — Improving Dementia Care in Primary Practice · NA · not yet recruiting
NCT07414550 — Radiotherapy for Refractory Hidradenitis Suppurativa · NA · not yet recruiting
NCT07402018 — Intra-aortic Balloon Counterpulsation (IABC) Compliance · recruiting
NCT07217197 — Respiratory Monitoring System That Detects & Predicts OIRD · NA · enrolling by invitation
NCT07145099 — The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05336786 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Thomas Jefferson University
Last refreshed: 4 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05336786.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing