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NCT05334836: FPPCN

Determination of Pancreatic Steatosis Prevalence and Correlation With High-risk Cyst Features

Recruiting now NA Last updated 11 August 2025
What this trial tests

NA trial testing MRI for pancreatic fat and liver fat quantitation in Pancreatic Steatosis in 236 participants. Currently enrolling.

Timeline
6 April 2022
Primary endpoint
30 April 2026
30 April 2026

Quick facts

Lead sponsorChinese University of Hong Kong
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposediagnostic
Enrollment236
Start date6 April 2022
Primary completion30 April 2026
Estimated completion30 April 2026
Sites1 location across Hong Kong

Drugs / interventions tested

Conditions studied

Sponsor

Chinese University of Hong Kong

Who can join

18 and older, any sex, with Pancreatic Steatosis or Pancreatic Cyst. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Pancreatic cancer is the fifth leading cause of cancer mortality in Hong Kong and the seventh leading cause of cancer mortality worldwide. In 2020, approximately 496000 new cases of pancreatic cancers were diagnosed globally . Pancreatic cancer is a highly fatal cancer with a case-fatality rate of 94.0% globally. In Hong Kong, both the incidence and mortality of pancreatic cancer have increased over the past decade. Due to the deep-seated location of pancreas, it is difficult to diagnose pancreatic cancer at an early stage, which in turn leads to delays in cancer treatment and poorer survival. Despite advances in oncologic treatment, the 5-year survival rate of metastatic pancreatic cancer remains poor (\~2.9%). As such, there has been growing interest to improve pancreatic cancer prevention and survival by: 1. reduction of modifiable risk factors (eg, cigarette smoking, obesity, diabetes), 2. screening for early detection of high-risk pre-malignant lesions in selected high-risks patients with strong family history of pancreatic cancer and/or certain germline mutations of pancreatic cancer susceptibility genes (eg, BRCA1, BRAC2, DNA mismatch repair genes in Lynch Syndrome, etc) by magnetic resonance imaging (MRI) or endoscopic ultrasound (EUS), and 3. surveillance of pre-malignant precursor lesions such as mucinous pancreatic cystic neoplasms (PCN) by imaging and/or EUS to identify high-risk neoplastic progression indicated for surgical resection.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Pancreatic Steatosis

Currently open trials in the same condition.

Other Chinese University of Hong Kong trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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