Last reviewed · How we verify
NCT05334134
COVID-19: Immunological Mechanisms in Multisystem Inflammatory Syndrome in Children
trial in Multisystem Inflammatory Syndrome in Children in 300 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | Rigshospitalet, Denmark |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 1 February 2020 |
| Primary completion | 31 December 2022 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across Denmark |
Conditions studied
- Multisystem Inflammatory Syndrome in Children — all drugs for Multisystem Inflammatory Syndrome in Children →
- COVID-19 — all drugs for COVID-19 →
- SARS-CoV-2 Infection — all drugs for SARS-CoV-2 Infection →
Sponsor
Rigshospitalet, Denmark
Who can join
Adults 1 Month to 17, any sex, with Multisystem Inflammatory Syndrome in Children or COVID-19. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study seeks to explore immunological mechanisms in patients with Multisystem Inflammatory Syndrome in Children (MIS-C) to improve the understanding of this pathogenesis of this disease. In a cohort of MIS-C patients diagnosed during the Wild type, Alpha, Delta and Omicron waves, research samples will be analyzed for whole-blood RNA expression, proteomics, inflammatory cytokines, cellular immune populations, autoantibodies, as well as host genetic markers.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children.
Nygaard U, Nielsen AB, Dungu KHS, Drici L, et al · · 2024 · cited 10× · PMID 38839859 · DOI 10.1038/s42003-024-06370-8
Verify or expand the search:
- PubMed search for NCT05334134
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Multisystem Inflammatory Syndrome in Children
Currently open trials in the same condition.
- NCT04844242 — MISC COVID-19 Study in Pediatric Population · recruiting
Other Rigshospitalet, Denmark trials
Trials by the same sponsor.
- NCT07401368 — Clinicians' Trust in AI-Based Fetal Growth Estimates · NA · not yet recruiting
- NCT07442357 — The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial · NA · not yet recruiting
- NCT07528729 — Alcohol as a Modifiable Risk Factor for Atrial Fibrillation · NA · not yet recruiting
- NCT07511439 — Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission · Phase 4 · not yet recruiting
- NCT07467187 — Invasive Home Ventilation in Denmark · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05334134 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rigshospitalet, Denmark
- Last refreshed: 19 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05334134.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing