NCT05331170 (VMR) is a Phase 2 clinical trial of Research Grade RG-RV in Asthma, sponsored by The University of Texas Medical Branch, Galveston.

Who is sponsoring NCT05331170?

NCT05331170 is sponsored by The University of Texas Medical Branch, Galveston.

What drugs are being tested in NCT05331170?

Interventions in NCT05331170: Research Grade RG-RV.

What condition does NCT05331170 study?

NCT05331170 studies Asthma, Allergic Rhinitis, Cat Allergy, Healthy.

Is NCT05331170 still recruiting?

NCT05331170 is currently recruiting now. Last updated 28 January 2025.

Last reviewed 2025-01-28 · How we verify

NCT05331170: VMR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Viral Mucosal Reprogramming

Recruiting now Phase 2 Last updated 28 January 2025

What this trial tests

Phase 2 trial testing Research Grade RG-RV in Asthma in 75 participants. Currently enrolling.

Timeline

27 April 2023

Primary endpoint
1 May 2027

1 May 2027

Quick facts

Lead sponsor	The University of Texas Medical Branch, Galveston
Phase	Phase 2
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	basic science
Enrollment	75
Start date	27 April 2023
Primary completion	1 May 2027
Estimated completion	1 May 2027
Sites	1 location across United States

Drugs / interventions tested

Research Grade RG-RV — full drug profile →

Conditions studied

Asthma — all drugs for Asthma →
Allergic Rhinitis — all drugs for Allergic Rhinitis →
Cat Allergy — all drugs for Cat Allergy →
Healthy — all drugs for Healthy →

Sponsor

The University of Texas Medical Branch, Galveston

Who can join

Adults 18 to 60, any sex, with Asthma or Allergic Rhinitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway remodeling in 25 healthy controls (HC), in 25 allergic rhinitis subjects (AR) with cat dander allergy, and in 25 allergic asthmatic subjects (AA) with cat dander allergy. Three groups (HC, AR, and AA) will undergo screening to establish clinical history, will undergo pulmonary function testing (spirometry), and will have blood drawn for clinical characterization (IgE, , ImmunoCAP, CBC and differential), and for assessing the presence of existing neutralizing antibody against RV16. Only those who meet criteria will be permitted to continue into the interventional and run-out phases of the study.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05331170 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The University of Texas Medical Branch, Galveston
Last refreshed: 28 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05331170.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing