NCT05328284 (PASTE) is a clinical trial of PASCAL leaflet repair system in Tricuspid Regurgitation, sponsored by LMU Klinikum.

Who is sponsoring NCT05328284?

NCT05328284 is sponsored by LMU Klinikum.

What drugs are being tested in NCT05328284?

Interventions in NCT05328284: PASCAL leaflet repair system.

What condition does NCT05328284 study?

NCT05328284 studies Tricuspid Regurgitation.

Is NCT05328284 still recruiting?

NCT05328284 is currently status unknown. Last updated 14 April 2022.

Last reviewed 2022-04-14 · How we verify

NCT05328284: PASTE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

PASCAL for Tricuspid Regurgitation - a European Registry

Status unknown Last updated 14 April 2022

What this trial tests

trial testing PASCAL leaflet repair system in Tricuspid Regurgitation in 1,000 participants. Status unknown.

Timeline

5 May 2021

Primary endpoint
30 May 2023

30 May 2024

Quick facts

Lead sponsor	LMU Klinikum
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	1,000
Start date	5 May 2021
Primary completion	30 May 2023
Estimated completion	30 May 2024
Sites	14 locations across Sweden, Switzerland, Germany

Drugs / interventions tested

PASCAL leaflet repair system

Conditions studied

Tricuspid Regurgitation — all drugs for Tricuspid Regurgitation →

Sponsor

LMU Klinikum — full company profile →

Who can join

18 and older, any sex, with Tricuspid Regurgitation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to investigate the safety and efficacy of the PASCAL leaflet repair system in the treatment of tricuspid regurgitation in a commercial use setting including all consecutive patients at the participating Centers in an observational fashion.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Transcatheter Valve Repair for Tricuspid Regurgitation: 1-Year Results From a Large European Real-World Registry.
Wild MG, Stolz L, Rosch S, Rudolph F, et al · · 2025 · cited 38× · PMID 39466215 · DOI 10.1016/j.jacc.2024.10.068
Transcatheter Management of Tricuspid Regurgitation: A Review of Contemporary Evidence.
Sammour YM, Anwaar MF, Cabral-Amador F, Garcia J, et al · · 2024 · cited 3× · PMID 39885934 · DOI 10.17925/hi.2024.18.2.4

Verify or expand the search:

Other recruiting trials for Tricuspid Regurgitation

Currently open trials in the same condition.

NCT07509658 — TriClip Japan Post-Approval Study · recruiting
NCT07042360 — Application of Comprehensive Non-invasive Assessment To Phenotype Tricuspid Regurgitation · recruiting
NCT06833476 — TTVR STRONG Under Coverage With Evidence Development (CED) Study · recruiting
NCT06836011 — A Multicenter Study on Atrioventricular Regurgitation in Transthyretin Amyloid Cardiomyopathy: Definition, Prevalence, a · recruiting
NCT07085650 — The Multi-center Study of Comprehensive Atrial Fibrillation Regurgitation and Recurrent Events Evaluation · recruiting

Other LMU Klinikum trials

Trials by the same sponsor.

NCT07072676 — The Use of Assistive Gait Devices Can Reduce the Risk of Falls in Patients With Neuromuscular Diseases Following a Train · NA · enrolling by invitation
NCT07159607 — Amino Acid PET-based Response Assessment in IDH-mutant Gliomas (APPEAR) · recruiting
NCT06600165 — Intraoperative Confocal Laser Scanning Microscopy With Use of AI for Optimized Surgical Excision of Basal Cell Carcinoma · recruiting
NCT07460531 — Assessment of Physical Activity and Cardiovascular Outcomes in Patients With Chronic Heart Failure · recruiting
NCT06605612 — Development and Validation of the FBIndex to Determine the Risk of Falls for Patients With Neuromuscular Disorders · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05328284 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by LMU Klinikum
Last refreshed: 14 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05328284.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing