Last reviewed · How we verify
NCT05321745: FMT
Fecal Microbiota Transplantation in Pediatric Crohn's Disease
NA trial testing Standardized FMT in Crohn Disease in 40 participants. Currently enrolling.
31 May 2026
Quick facts
| Lead sponsor | Biao Zou |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 22 March 2022 |
| Primary completion | 31 May 2026 |
| Estimated completion | 31 May 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Standardized FMT
Conditions studied
- Crohn Disease — all drugs for Crohn Disease →
Sponsor
Biao Zou
Who can join
Adults 2 to 16, any sex, with Crohn Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will test the safety and effectiveness of fecal microbiota transplantation (FMT) plus partial enteral nutrition (PEN) in refractory pediatric Crohn's disease (CD) who have failed conventional treatment
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Current Trends and Challenges of Fecal Microbiota Transplantation-An Easy Method That Works for All?
Almeida C, Oliveira R, Baylina P, Fernandes R, et al · · 2022 · cited 34× · PMID 36359265 · DOI 10.3390/biomedicines10112742 -
Fecal microbiota transplantation restores gut microbiota diversity in children with active Crohn's disease: a prospective trial.
Zou B, Liu S, Dong C, Shen H, et al · · 2025 · cited 9× · PMID 40050917 · DOI 10.1186/s12967-024-05832-1
Verify or expand the search:
- PubMed search for NCT05321745
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Standardized FMT
Trials testing the same drug.
- NCT04890405 — Clinical Study of Selective Fecal Microbiota Transplantation in the Treatment of Irritable Bowel Syndrome. · NA · unknown
Other recruiting trials for Crohn Disease
Currently open trials in the same condition.
- NCT06953791 — Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Pat · Phase 2 · recruiting
- NCT07310095 — A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD) · Phase 4 · recruiting
- NCT07364734 — Epidemiological Characteristics and Efficacy Evaluation of Difficult-To-Treat Crohn's Disease · recruiting
- NCT07170462 — Cranberry and Gut Health in Crohn's Disease · EARLY_PHASE1 · recruiting
- NCT07196722 — A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease · Phase 2, PHASE3 · recruiting
Other Biao Zou trials
Trials by the same sponsor.
- NCT05679622 — Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis (UC) · NA · recruiting
- NCT05753774 — Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05321745 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Biao Zou
- Last refreshed: 4 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05321745.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing