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NCT05320029

Disposable Powered Articulating Linear Cutter Stapler in Gastrointestinal Tissue Cutting and Anastomosis

Completed NA Results posted Last updated 14 December 2023
What this trial tests

NA trial testing Disposable Powered Articulating Endoscopic Linear Cutter Stapler in Gastrointestinal Neoplasm in 164 participants. Completed in 20 January 2022.

Timeline
30 August 2018
Primary endpoint
11 February 2020
20 January 2022

Quick facts

Lead sponsorFengh Medical Co., Ltd.
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposetreatment
Enrollment164
Start date30 August 2018
Primary completion11 February 2020
Estimated completion20 January 2022
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Fengh Medical Co., Ltd.

Who can join

Adults 18 to 75, any sex, with Gastrointestinal Neoplasm. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Participants With Anastomosis Success Primary · During surgery

The transection and anastomosis of lung tissues are performed during the operation. The device is withdrawn after successful triggering. The cutting staple line is carefully checked for integrity, air leakage and bleeding. Anastomosis is considered as successful if all anastomotic rings are intact without leakage or bleeding, otherwise it is considered as failure. If necessary, the gas injection method is used to inspect whether there is bubble overflow at anastomotic stoma. If there is no bubble overflow, it is recorded as successful anastomosis; if there is obvious bubble overflow, it is rec

GroupValue95% CI
Disposable Powered Articulating Endoscopic Linear Cutter Stapler80
Echelon Flex POWERED Articulating Endoscopic Linear Cutters80

Adverse events — posted to ClinicalTrials.gov

Time frame: 30 days. Reporting threshold: 0%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Disposable Powered Articulating Endoscopic Linear Cutter Stapler
Serious: 11/80 (14%)
Deaths: 0/80
Echelon Flex POWERED Articulating Endoscopic Linear Cutters
Serious: 9/80 (11%)
Deaths: 1/80

Serious adverse events (12 terms)

ReactionSystemDisposable Powered Articul…Echelon Flex POWERED Artic…
Intra-abdominal infectionInfections and infestations
gastric retentionGastrointestinal disorders
DeathGeneral disorders
Eating obstructionGastrointestinal disorders
Esophagojejunostomotic fistulaGastrointestinal disorders
Infection of incisional woundInfections and infestations
The anastomosis is narrowGastrointestinal disorders
Pelvic infectionInfections and infestations
IleusGastrointestinal disorders
Subdiaphragmatic abscessInfections and infestations
Hemorrhage of digestive tractGastrointestinal disorders
CholecystolithiasisHepatobiliary disorders
Other adverse events (4 terms — click to expand)

ReactionSystemDisposable Powered Articul…Echelon Flex POWERED Artic…
hypoproteinemiaMetabolism and nutrition disorders
feverGeneral disorders
incision painInjury, poisoning and procedural complications
otherGeneral disorders

Most-reported serious reactions: Intra-abdominal infection, gastric retention, Death, Eating obstruction, Esophagojejunostomotic fistula, Infection of incisional wound, The anastomosis is narrow, Pelvic infection.

Data from ClinicalTrials.gov NCT05320029 adverse events section.

Sponsor's own description

To evaluate whether the anastomosis success rate of the main effectiveness evaluation indexes is not inferior to the similar products produced by Johnson \& Johnson when the Fengh Disposable Powered Articulating Endoscopic Linear Cutter Stapler Used for Gastrointestinal Tissue Cutting and Anastomosis

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Disposable Powered Articulating Endoscopic Linear Cutter Stapler

Trials testing the same drug.

Other recruiting trials for Gastrointestinal Neoplasm

Currently open trials in the same condition.

Other Fengh Medical Co., Ltd. trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05320029.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing