NCT05314660 is a Phase 4 clinical trial of 38 % silver diamine fluoride in Caries Arrest, sponsored by Mansoura University.

Who is sponsoring NCT05314660?

NCT05314660 is sponsored by Mansoura University.

What drugs are being tested in NCT05314660?

Interventions in NCT05314660: 38 % silver diamine fluoride, Atraumatic restorative technique, Ultra conservative dentistry.

What condition does NCT05314660 study?

NCT05314660 studies Caries Arrest.

Is NCT05314660 still recruiting?

NCT05314660 is currently completed. Last updated 21 April 2022.

Last reviewed 2022-04-21 · How we verify

NCT05314660

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Arresting Active Dentine Lesions and Quality of Life Among a Group of Preschool Children

Completed Phase 4 Last updated 21 April 2022

What this trial tests

Phase 4 trial testing 38 % silver diamine fluoride in Caries Arrest in 135 participants. Completed in 15 March 2022.

Timeline

15 January 2020

Primary endpoint
15 January 2022

15 March 2022

Quick facts

Lead sponsor	Mansoura University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	135
Start date	15 January 2020
Primary completion	15 January 2022
Estimated completion	15 March 2022
Sites	1 location across Egypt

Drugs / interventions tested

38 % silver diamine fluoride — full drug profile →
Atraumatic restorative technique
Ultra conservative dentistry

Conditions studied

Caries Arrest — all drugs for Caries Arrest →

Sponsor

Mansoura University

Who can join

Adults 3 to 5, any sex, with Caries Arrest. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Testing 3 different caries arresting techniques and the quality of life of a group of preschool children in Mansoura city, Egypt.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults.
Worthington HV, Lewis SR, Glenny AM, Huang SS, et al · · 2024 · cited 8× · PMID 39508296 · DOI 10.1002/14651858.cd012718.pub2
Arresting Active Carious Lesions Using Minimal Intervention Dentistry among a Group of Preschool Children: A Randomized Controlled Clinical Trial.
Hamza BE, Attia NM, Abdellatif AM, Hegazy SA. · · 2024 · cited 3× · PMID 39664835 · DOI 10.5005/jp-journals-10005-2927

Verify or expand the search:

Other Mansoura University trials

Trials by the same sponsor.

NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
NCT07509567 — Conventional Palatal Crib Versus Bonded Spurs for Anterior Open Bite Treatment · NA · not yet recruiting
NCT07393178 — Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones · NA · not yet recruiting
NCT07436182 — Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. · Phase 4 · not yet recruiting
NCT07534943 — Effectiveness of Oleanolic Acid as Intracanal Medicament on Infectious/Inflammatory Contents in Teeth With Apical Period · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05314660 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mansoura University
Last refreshed: 21 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05314660.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing