NCT05313399 is a Phase 3 clinical trial of Palatal Crib in Anterior Open Bite, sponsored by Reem Hatem Shams.

Who is sponsoring NCT05313399?

NCT05313399 is sponsored by Reem Hatem Shams.

What drugs are being tested in NCT05313399?

Interventions in NCT05313399: Palatal Crib, bonded spur.

What condition does NCT05313399 study?

NCT05313399 studies Anterior Open Bite.

Is NCT05313399 still recruiting?

NCT05313399 is currently status unknown. Last updated 6 April 2022.

Last reviewed 2022-04-06 · How we verify

NCT05313399

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Palatal Crib Versus Bonded Spurs in Early Treatment of Anterior Open Bite Caused by Non-nutritive Sucking Habits: RCT

Status unknown Phase 3 Last updated 6 April 2022

What this trial tests

Phase 3 trial testing Palatal Crib in Anterior Open Bite in 30 participants. Status unknown.

Timeline

1 April 2022

Primary endpoint
1 April 2023

1 May 2023

Quick facts

Lead sponsor	Reem Hatem Shams
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	30
Start date	1 April 2022
Primary completion	1 April 2023
Estimated completion	1 May 2023

Drugs / interventions tested

Palatal Crib
bonded spur

Conditions studied

Anterior Open Bite — all drugs for Anterior Open Bite →

Sponsor

Reem Hatem Shams

Who can join

Adults 6 to 11, any sex, with Anterior Open Bite. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study evaluates the effects of palatal crib versus bonded spurs in the early treatment of anterior open bite caused by non-nutritive sucking habits.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Comparing skeletal and dentoalveolar effects of fixed palatal crib and bonded spurs in early management of anterior open bite associated with non-nutritive sucking habits: a randomized clinical trial.
Shams RH, Ali MM, Kabel N, El Khadem AH. · · 2026 · PMID 40750942 · DOI 10.1007/s40368-025-01086-7
Comparing Skeletal and Dentoalveolar Effects of Fixed Palatal Crib and Bonded Spurs in Early Management of Anterior Open Bite Associated with Non-Nutritive Sucking Habits: A Randomised Clinical Trial
Shams R, Ali M, Kabel N, Elkhadem A. · · 2025 · DOI 10.21203/rs.3.rs-6660641/v1

Verify or expand the search:

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05313399 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Reem Hatem Shams
Last refreshed: 6 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05313399.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing