Last reviewed · How we verify
NCT05311982: TDCSinASD
Transcranial Direct Current Stimulation in Autistic Spectrum Disorder
NA trial testing DLPFC-R (F4) TDCS in Autistic Disorders Spectrum in 12 participants. Completed in 30 September 2021.
30 July 2021
Quick facts
| Lead sponsor | Federal University of Paraíba |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 12 |
| Start date | 1 March 2021 |
| Primary completion | 30 July 2021 |
| Estimated completion | 30 September 2021 |
| Sites | 2 locations across Brazil |
Drugs / interventions tested
- DLPFC-R (F4) TDCS
- DLPFC-L (F3) and DLPFC-R (F4) TDCS
- sham-tDCS
Conditions studied
- Autistic Disorders Spectrum — all drugs for Autistic Disorders Spectrum →
Sponsor
Federal University of Paraíba
Who can join
Adults 5 to 18, any sex, with Autistic Disorders Spectrum. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To understand the changes in the resting electroencephalogram (EEG) brain networks of children and adolescents with autistic spectrum disorder (ASD) induced by transcranial direct current stimulation (tDCS), we asked two questions. First: how can tDCS modulate the expression of neural network dynamics? Second: how can tDCS modulate functional connections at specific frequencies? We hypothesized that the tDCS mechanism results in increased cortical frequencies in the areas under the anode, which may reflect an increase in synaptic connectivity, and that this tDCS-related increase changes connection profiles at specific frequencies important for ASD, indicating improvement in symptoms. To verify this improvement, the researchers used the Autism Treatment Evaluation Checklist (ATEC) after an intervention, comparing baseline scores with post-treatment scores.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05311982
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Autistic Disorders Spectrum
Currently open trials in the same condition.
- NCT05910502 — Project AFECT (Autism Family Empowerment Coaching and Training Program) · NA · active not recruiting
- NCT05035511 — A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders · NA · recruiting
- NCT03672266 — Studies of Brain and Body Interaction · recruiting
Other Federal University of Paraíba trials
Trials by the same sponsor.
- NCT07192003 — Immediate Effects of Flossband and Mobilization With Movement on Shoulder Mobility in Volleyball Athletes · NA · not yet recruiting
- NCT06827379 — Acute Effects of Inspiratory Muscle Training on Peripheral Muscle Metabolism and Autonomic Response in COPD Patients · NA · enrolling by invitation
- NCT06542666 — Cognitive Functional Therapy for Chronic Shoulder Pain: Pilot and Feasibility Study · NA · recruiting
- NCT06661681 — Cognitive Functional Therapy for Treating Individuals With Chronic Shoulder Pain · NA · recruiting
- NCT06384027 — Effects of Non-invasive Ventilation on Function Diaphragmatic and Caval Distension · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05311982 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Federal University of Paraíba
- Last refreshed: 5 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05311982.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing