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NCT05311150: NABS
An RCT of NBI vs. White Light Guided Endobronchial Biopsy in Suspected Sarcoidosis
NA trial testing Narrow band imaging bronchoscopy guided endobronchial biopsy in Sarcoidosis, Pulmonary in 150 participants. Completed in 15 February 2023.
31 January 2023
Quick facts
| Lead sponsor | Post Graduate Institute of Medical Education and Research, Chandigarh |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 150 |
| Start date | 1 January 2022 |
| Primary completion | 31 January 2023 |
| Estimated completion | 15 February 2023 |
| Sites | 1 location across India |
Drugs / interventions tested
- Narrow band imaging bronchoscopy guided endobronchial biopsy
- White light bronchscopy guided endobronchial biopsy
Conditions studied
- Sarcoidosis, Pulmonary — all drugs for Sarcoidosis, Pulmonary →
Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
Who can join
18 and older, any sex, with Sarcoidosis, Pulmonary. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In the diagnosis of patients with sarcoidosis, there is paucity of literature on the diagnostic yield of the endobronchial biopsies obtained with narrow band imaging (NBI) bronchoscopy. The present study aims to compare the diagnostic yield of endobronchial biopsyperformed under direct narrow band imaging or white light bronchoscopy guidance in suspected sarcoidosis.We hypothesize that the use of NBI will improve the yield of endobronchial biopsy in patients with sarcoidosis.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
High-Definition Videobronchoscopy for the Diagnosis of Airway Involvement in Sarcoidosis: The Enhance Sarcoidosis Multicenter Study.
Livi V, Sivokozov I, Annema JT, Candoli P, et al · · 2023 · cited 6× · PMID 37121391 · DOI 10.1016/j.chest.2023.04.034 -
A randomized trial of narrow band imaging for performing airway mucosal biopsy in pulmonary sarcoidosis (NABS).
Rathi K, Dogra P, Agarwal R, Singh Sehgal I, et al · · 2025 · PMID 41026031 · DOI 10.36141/svdld.v42i3.16418
Verify or expand the search:
- PubMed search for NCT05311150
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sarcoidosis, Pulmonary
Currently open trials in the same condition.
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- NCT06479603 — RCT of Nintedanib in Fibrotic Sarcoidosis · Phase 4 · recruiting
- NCT05746039 — Feasibility of Semaglutide in Advanced Lung Disease · Phase 1, PHASE2 · recruiting
- NCT05291468 — the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis · NA · active not recruiting
- NCT05567133 — Risk Indicators of Sarcoidosis Evolution-Unified Protocol · recruiting
Other Post Graduate Institute of Medical Education and Research, Chandigarh trials
Trials by the same sponsor.
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- NCT07280390 — Microplastics, Cirrhosis and Portal Hypertension · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05311150 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Post Graduate Institute of Medical Education and Research, Chandigarh
- Last refreshed: 29 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05311150.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing