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NCT05308914
Self-Management and Resilience Trajectories in African American Adults With Hypertension
trial in Hypertension in 125 participants. Completed in 21 March 2025.
21 March 2025
Quick facts
| Lead sponsor | Case Western Reserve University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 125 |
| Start date | 1 March 2022 |
| Primary completion | 21 March 2025 |
| Estimated completion | 21 March 2025 |
| Sites | 1 location across United States |
Conditions studied
- Hypertension — all drugs for Hypertension →
- Self-Management — all drugs for Self-Management →
- Quality of Life — all drugs for Quality of Life →
- Compliance, Medication — all drugs for Compliance, Medication →
Sponsor
Case Western Reserve University
Who can join
25 and older, any sex, with Hypertension or Self-Management. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hypertension (HTN) rates have increased worldwide, but the most significant increase in the incidence of morbidity and mortality has been in African Americans (AA)1,2 (43% vs 27% for other U.S. population groups). Despite evidence of positive benefits from lifestyle modification (healthy diet, reduced sodium intake, increased physical activity, smoking cessation) and prescribed antihypertensive therapy (AHT) many AA with HTN do not adhere to their treatment regimens. Consistent, effective lifelong self-management is required to sustain optimal BP control and thus reduce morbidity and mortality. Self-managing HTN to a blood pressure (BP) \<130/80 mm Hg presents challenges such as juggling multiple medications and health care providers, dealing with complex recommendations and treatment regimens, and coping with negative emotional states. Few studies have examined the biopsychosocial mechanisms that foster effective HTN self-management and resilience among AA living with HTN. Understanding the mechanisms that influence HTN self-management and resilience in AA holds the promise of new modifiable targets for behavior-change interventions. This study explores the relationship among resilience precursors on hypertension (HTN) self-management behaviors, stress response, and the effects that these relationships have on health outcomes-health-related quality of life (HRQOL) and blood pressure (BP) in African Americans (AA) with HTN over a 6-month period.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Resilience and Self-Management of Hypertension in African American Adults Using a Conceptualized Resilience Framework: An Exploratory Analysis.
Still CH, Ruksakulpiwat S. · · 2024 · cited 2× · PMID 38905621 · DOI 10.1097/nnr.0000000000000743
Verify or expand the search:
- PubMed search for NCT05308914
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05308914 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Case Western Reserve University
- Last refreshed: 26 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05308914.
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