NCT05306158

Dual Use Approach Bias Training for Nicotine Addiction

Completed NA Last updated 27 March 2025

What this trial tests

NA trial testing CC+ECIG Condition in Tobacco Smoking in 107 participants. Completed in 30 November 2024.

Timeline

3 October 2022

Primary endpoint
30 September 2024

30 November 2024

Quick facts

Lead sponsor	University of Houston
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	107
Start date	3 October 2022
Primary completion	30 September 2024
Estimated completion	30 November 2024
Sites	1 location across United States

Drugs / interventions tested

• CC+ECIG Condition
• CC Condition
• Sham Condition

Conditions studied

• Tobacco Smoking — all drugs for Tobacco Smoking →
• Electronic Cigarette Use — all drugs for Electronic Cigarette Use →
• Substance Use — all drugs for Substance Use →

Sponsor

University of Houston

Who can join

18 and older, any sex, with Tobacco Smoking or Electronic Cigarette Use. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The present project will evaluate the initial efficacy of approach bias retraining among dual combustible cigarette (CC) and electronic cigarette (ECIG) users. The study employs a randomized controlled design to follow 90 experienced dual CC/ECIG users motivated to quit nicotine as they engage in a self-guided quit attempt following approach bias retraining.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Study protocol for approach bias retraining for nicotine addiction among dual combustible and electronic cigarette users.
   Clausen B, Rinck M, Nizio P, Matoska CT, et al · · 2023 · PMID 36905980 · DOI 10.1016/j.cct.2023.107145