Last reviewed · How we verify
NCT05293418: MDR_in_Fiera
Incidence of Colonization by Multidrug-resistant Organisms in Mechanically Ventilated Patients With Severe COVID-19
trial testing data collection in COVID-19 in 435 participants. Completed in 30 September 2022.
30 May 2021
Quick facts
| Lead sponsor | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 435 |
| Start date | 1 October 2020 |
| Primary completion | 30 May 2021 |
| Estimated completion | 30 September 2022 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- data collection — full drug profile →
Conditions studied
- COVID-19 — all drugs for COVID-19 →
- Bacterial Infections — all drugs for Bacterial Infections →
- Colonization, Asymptomatic — all drugs for Colonization, Asymptomatic →
Sponsor
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Who can join
18 and older, any sex, with COVID-19 or Bacterial Infections. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Retrospective single-center cohort study to evaluate the incidence of colonization by multidrug-resistant organisms (MDRO) in mechanically ventilated patients admitted to a large intensive care unit (ICU) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the second wave of COVID-19 pandemic (October 2020-May 2021) in Lombardy, Italy. As secondary outcomes, the study evaluates the overall incidence of infections during the ICU stay and assesses the risk factors associated to bacterial superinfection and MDRO colonization.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Genomic Characterization of Carbapenem-Resistant <i>Acinetobacter baumannii</i> (CRAB) in Mechanically Ventilated COVID-19 Patients and Impact of Infection Control Measures on Reducing CRAB Circulation during the Second Wave of the SARS-CoV-2 Pandemic in Milan, Italy.
Mangioni D, Fox V, Chatenoud L, Bolis M, et al · · 2023 · cited 18× · PMID 36976013 · DOI 10.1128/spectrum.00209-23 -
Multidrug-Resistant Bacterial Colonization and Infections in Large Retrospective Cohort of Mechanically Ventilated COVID-19 Patients<sup>1</sup>.
Mangioni D, Chatenoud L, Colombo J, Palomba E, et al · · 2023 · cited 4× · PMID 37486196 · DOI 10.3201/eid2908.230115
Verify or expand the search:
- PubMed search for NCT05293418
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of data collection
Trials testing the same drug.
- NCT07437495 — Women's Knowledge of Contraception During the Postpartum Period · active not recruiting
- NCT07424937 — Prevalence of Regular Gynecological Follow-up Among Women of Childbearing Age · completed
- NCT07440082 — Resumption of Sexual Intercourse in the Postpartum Period: Women's Experiences · completed
- NCT07241299 — Understanding Chronic Treatments by Patients Over 65 Years of Age · recruiting
- NCT07338955 — Validating and Assessing Reliability · recruiting
Other recruiting trials for COVID-19
Currently open trials in the same condition.
- NCT07183709 — Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults · Phase 1 · active not recruiting
- NCT07300839 — A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age · Phase 3 · active not recruiting
- NCT07221162 — A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes · Phase 1 · recruiting
- NCT07215520 — Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults · Phase 2 · recruiting
- NCT07222384 — A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That A · Phase 3 · active not recruiting
Other Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico trials
Trials by the same sponsor.
- NCT07492433 — Risk Factors, Incidence, and Clinical Impact of Intraluminal Thrombosis Following FET and TEVAR · not yet recruiting
- NCT07402174 — EIT- Guided Lung Recruitment in pARDS · NA · not yet recruiting
- NCT07234097 — The Influence of Music on perceiVed paIn and leVels of Anxiety whiLe unDergoing transperIneal Prostate Biopsy: the VIVAL · NA · not yet recruiting
- NCT07317193 — DEFINING THE GENETIC DRIVERS OF ADULT-ONSET CHOLESTATIC LIVER DISEASE · NA · recruiting
- NCT07487961 — Assess Abdominal Aortic Diameter in Females · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05293418 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- Last refreshed: 7 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05293418.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing