Last reviewed · How we verify
NCT05291247: Shockwave DES
Shockwave IVL + DES
trial testing Peripheral lithotripsy system (Shockwave Medical) in Peripheral Arterial Disease in 50 participants. Completed in 10 February 2026.
23 September 2025
Quick facts
| Lead sponsor | Marc Bosiers, MD |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 22 July 2022 |
| Primary completion | 23 September 2025 |
| Estimated completion | 10 February 2026 |
| Sites | 6 locations across Germany |
Drugs / interventions tested
- Peripheral lithotripsy system (Shockwave Medical)
Conditions studied
- Peripheral Arterial Disease — all drugs for Peripheral Arterial Disease →
- Superficial Femoral Artery Stenosis — all drugs for Superficial Femoral Artery Stenosis →
- Calcifications Vascular — all drugs for Calcifications Vascular →
Sponsor
Marc Bosiers, MD
Who can join
Adults 21 to 85, any sex, with Peripheral Arterial Disease or Superficial Femoral Artery Stenosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this clinical investigation is to evaluate, in a controlled setting, the 12 months safety and efficacy of the combination of Shockwave Intravascular Lithotripsy and a polymer coated Drug Eluting Stent device, for PACSS 3 and PACSS 4 calcified femoropopliteal disease.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Vascular calcification: from the perspective of crosstalk.
Yang S, Zeng Z, Yuan Q, Chen Q, et al · · 2023 · cited 13× · PMID 37851172 · DOI 10.1186/s43556-023-00146-y
Verify or expand the search:
- PubMed search for NCT05291247
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Peripheral Arterial Disease
Currently open trials in the same condition.
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- NCT07336381 — Replexa+ Shortwave Diathermy Device for Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuropathy · NA · recruiting
- NCT07076082 — Vascular Trial Associated Registry Pilot · Phase 4 · recruiting
- NCT06308562 — Fuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial Disease · NA · recruiting
Other Marc Bosiers, MD trials
Trials by the same sponsor.
- NCT03987035 — BGP Stent as Bridging Stent in FEVAR · NA · completed
- NCT03982940 — BGP+ Stent as Bridging Stent in BEVAR · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05291247 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Marc Bosiers, MD
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05291247.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing