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NCT05287633
Proton Pump Inhibitors Effects on Dyspepsia During Ramadan Fasting
Phase 1, PHASE2 trial testing Esomeprazole in Dyspepsia in 500 participants. Completed in 30 December 2024.
15 December 2020
Quick facts
| Lead sponsor | University of Monastir |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 500 |
| Start date | 20 January 2020 |
| Primary completion | 15 December 2020 |
| Estimated completion | 30 December 2024 |
| Sites | 1 location across Tunisia |
Drugs / interventions tested
- Esomeprazole (esomeprazole) — full drug profile →
- Placebo
Conditions studied
- Dyspepsia — all drugs for Dyspepsia →
Sponsor
University of Monastir
Who can join
18 and older, any sex, with Dyspepsia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
evaluate the interest of proton pump inhibitors in subjects with or with GI symptoms who intend to observe fasting in Ramadan. The investigators will compare the effectiveness of proton pump inhibitors to prevent or reduce the signs of dyspepsia during Ramadan compared to placebo.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Randomized trial of the effect of esomeprazole on functional dyspepsia during Ramadan fasting.
Hadrich S, Lamti F, Trabelsi I, Dhaoui R, et al · · 2025 · PMID 41120363 · DOI 10.1038/s41598-025-17532-x
Verify or expand the search:
- PubMed search for NCT05287633
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05287633 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Monastir
- Last refreshed: 25 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05287633.
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