NCT05283941 is a NA clinical trial of Pistachio Group in Macular Degeneration, sponsored by Tufts University.

Who is sponsoring NCT05283941?

NCT05283941 is sponsored by Tufts University.

What drugs are being tested in NCT05283941?

Interventions in NCT05283941: Pistachio Group.

What condition does NCT05283941 study?

NCT05283941 studies Macular Degeneration, Retinal Degeneration, Retinal Diseases, Eye Diseases.

Is NCT05283941 still recruiting?

NCT05283941 is currently status unknown. Last updated 9 March 2023.

Last reviewed 2023-03-09 · How we verify

NCT05283941

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pistachios and Neural Macular Pigment

Status unknown NA Last updated 9 March 2023

What this trial tests

NA trial testing Pistachio Group in Macular Degeneration in 40 participants. Status unknown.

Timeline

10 June 2022

Primary endpoint
30 November 2023

30 November 2023

Quick facts

Lead sponsor	Tufts University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	40
Start date	10 June 2022
Primary completion	30 November 2023
Estimated completion	30 November 2023
Sites	1 location across United States

Drugs / interventions tested

Pistachio Group

Conditions studied

Macular Degeneration — all drugs for Macular Degeneration →
Retinal Degeneration — all drugs for Retinal Degeneration →
Retinal Diseases — all drugs for Retinal Diseases →
Eye Diseases — all drugs for Eye Diseases →

Sponsor

Tufts University

Who can join

Adults 40 to 70, any sex, with Macular Degeneration or Retinal Degeneration. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss as people age. Studies have shown that lutein and zeaxanthin, nutrients found in green leafy vegetables and egg yolks, can help protect against AMD in older adults. These nutrients form a pigment in the retina (macular pigment) that can help protect the retina from light damage. Pistachios are rich sources of both lutein and zeaxanthin; thus, dietary intake of pistachios could serve as a beneficial food source for eye health.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pistachio Consumption Increases Macular Pigment Optical Density in Healthy Adults: A Randomized Controlled Trial.
Scott TM, Ogunbodede O, McKay DL, Johnson EJ. · · 2025 · cited 3× · PMID 39426460 · DOI 10.1016/j.tjnut.2024.10.022

Verify or expand the search:

Other trials of Pistachio Group

Trials testing the same drug.

NCT03120455 — Effects of Almond Versus Pistachio on Weight Loss · NA · completed

Other recruiting trials for Macular Degeneration

Currently open trials in the same condition.

NCT07440225 — A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, PHASE3 · recruiting
NCT07085533 — Natural History Study of Inherited Retinal Diseases · recruiting
NCT06805474 — A Prospective Observational Study to Assess the Reliability and Validity of the MLSDT · recruiting
NCT06779773 — A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy · recruiting
NCT06635148 — A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Se · Phase 2 · recruiting

Other Tufts University trials

Trials by the same sponsor.

NCT07249242 — Healing Outcomes of Peri-implant Soft Tissues With Different Healing Abutments · NA · recruiting
NCT07099131 — Effective Interventions to Overcome Severe Gag Reflex · EARLY_PHASE1 · not yet recruiting
NCT06428630 — Systemic Absorption of Dexamethasone Oral Rinse in Patients With Oral Lichen Planus · EARLY_PHASE1 · withdrawn
NCT06526221 — Evaluating Urine Isoniazid Testing to Detect Nonadherence to Tuberculosis Medications in India · NA · not yet recruiting
NCT06352645 — Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05283941 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tufts University
Last refreshed: 9 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05283941.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing