Last reviewed · How we verify
NCT05279495: CNXR-001D
Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers
NA trial testing In a double-blinded fashion, 250 mg CANNAXR cream in Photoaging in 20 participants. Completed in 15 May 2023.
1 April 2023
Quick facts
| Lead sponsor | MINO Labs, LLC |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 20 |
| Start date | 15 January 2023 |
| Primary completion | 1 April 2023 |
| Estimated completion | 15 May 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- In a double-blinded fashion, 250 mg CANNAXR cream
- Topical VEHICLE cream
Conditions studied
- Photoaging — all drugs for Photoaging →
Sponsor
MINO Labs, LLC
Who can join
Adults 22 to 65, any sex, with Photoaging. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Ultraviolet light A (UVA) causes oxidization of guanine to mutagenic 8-Oxoguanine (8-OxoG) and the most frequent and best characterized mutation in mitochondrial DNA (mtDNA), a deletion of 4,977 base pairs, called the "common deletion", a marker of photoaging.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Topical nanoencapsulated cannabidiol cream as an innovative strategy combating UV-A-induced nuclear and mitochondrial DNA injury: A pilot randomized clinical study.
McCormick E, Han H, Abdel Azim S, Whiting C, et al · · 2024 · cited 8× · PMID 39025264 · DOI 10.1016/j.jaad.2024.06.088
Verify or expand the search:
- PubMed search for NCT05279495
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Photoaging
Currently open trials in the same condition.
- NCT06029725 — RFMN in Combination With 1927 nm Thulium Laser for Treating Photoaged Skin · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05279495 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by MINO Labs, LLC
- Last refreshed: 8 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05279495.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing