Last reviewed · How we verify
NCT05279248
The Immunogenicity and Safety of the Vaccination of Human Papillomavirus Vaccine and Measles-Mumps-Rubella Vaccine
Phase 4 trial testing HPV+MMR(0d),HPV(6m) in Human Papilloma Virus Infection Type 16 in 300 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | Zhejiang Provincial Center for Disease Control and Prevention |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 300 |
| Start date | 25 August 2021 |
| Primary completion | 31 December 2022 |
| Estimated completion | 20 June 2023 |
| Sites | 2 locations across China |
Drugs / interventions tested
- HPV+MMR(0d),HPV(6m) — full drug profile →
- HPV(0d),HPV(6m),MMR(7m) — full drug profile →
- MMR(0d),HPV(1m),HPV(7m) — full drug profile →
Conditions studied
- Human Papilloma Virus Infection Type 16 — all drugs for Human Papilloma Virus Infection Type 16 →
- Human Papilloma Virus Infection Type 18 — all drugs for Human Papilloma Virus Infection Type 18 →
- Measles — all drugs for Measles →
- Rubella — all drugs for Rubella →
Sponsor
Zhejiang Provincial Center for Disease Control and Prevention — full company profile →
Who can join
Adults 13 to 14, female only, with Human Papilloma Virus Infection Type 16 or Human Papilloma Virus Infection Type 18. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the immunogenicity and safety of Recombinant Human Papillomavirus Bivalent (Types 16,18) Vaccine (Escherichia coli) (HPV)and Measles Mumps and Rubella Combined Vaccine, Live(MMR)
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Therapeutic cancer vaccines: From biological mechanisms and engineering to ongoing clinical trials.
Sobhani N, Scaggiante B, Morris R, Chai D, et al · · 2022 · cited 57× · PMID 35759856 · DOI 10.1016/j.ctrv.2022.102429 -
Human papillomavirus (HPV) vaccination for the prevention of cervical cancer and other HPV-related diseases: a network meta-analysis.
Bergman H, Henschke N, Arevalo-Rodriguez I, Buckley BS, et al · · 2025 · cited 2× · PMID 41276263 · DOI 10.1002/14651858.cd015364.pub2
Verify or expand the search:
- PubMed search for NCT05279248
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Human Papilloma Virus Infection Type 16
Currently open trials in the same condition.
- NCT07407569 — Developing a First-void Urine-based Infection Model to Study HPV-specific Antibody-virion Interaction Before and After H · Phase 2 · recruiting
- NCT05669911 — Development of a Self-collection Device for Cervical Cancer Screening · NA · active not recruiting
Other Zhejiang Provincial Center for Disease Control and Prevention trials
Trials by the same sponsor.
- NCT07281677 — Immunogenicity and Safety of Sequential 2vHPV-9vHPV Vaccination in Girls Aged 9-14 Years · Phase 4 · recruiting
- NCT05373030 — Sequential Immunization With Recombinant Adenovirus Type-5-vectored COVID-19 Vaccine in Health Adults Based on 3 Doses I · Phase 4 · unknown
- NCT04817917 — Seroprevalence of Neutralizing Antibodies Against Japanese Encephalitis Virus Among 6 Years Old Children With 5 Differen · Phase 4 · unknown
- NCT04576910 — Immunogenicity and Safety of the Booster Dose of Polio Vaccine With Different Primary Sequential Schedules in China · Phase 4 · completed
- NCT04133584 — The Immunogenicity and Safety of the Vaccination of Inactivated Enterovirus 71 Vaccine and Seasonal Influenza Vaccine · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05279248 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zhejiang Provincial Center for Disease Control and Prevention
- Last refreshed: 29 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05279248.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing