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NCT05279014

Fasted Exercise and LDL-C

Completed NA Last updated 27 March 2025
What this trial tests

NA trial testing Meal timing in Cardiovascular Diseases in 29 participants. Completed in 30 August 2024.

Timeline
30 March 2022
Primary endpoint
13 August 2024
30 August 2024

Quick facts

Lead sponsorUniversity of Bath
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposebasic science
Enrollment29
Start date30 March 2022
Primary completion13 August 2024
Estimated completion30 August 2024
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Bath

Who can join

Adults 25 to 60, any sex, with Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiovascular disease (CVD) is the leading cause of death in the UK and worldwide with low density lipoprotein cholesterol (LDL-C) being one of the most important modifiable risk factors. Physical activity is inexpensive and research shows that it consistently improves high density lipoprotein and triglyceride concentrations. However, fails to improve LDL-C concentrations. Preliminary research suggests fasted exercise could potentially improve LDL-C concentrations. The majority of research in these areas have also mostly been done in males with the results generalised to females. As it is known that lipid metabolism and CVD risk is different between sexes it is possible that the response to fasted exercise may also be different between sexes. This aim of this study is to assess the effect of physical activity performed before or after a meal on plasma LDL-C concentrations in men and women and explore sex differences. The study will also assess the effect of fasted exercise on other CVD risk factors.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The effect of exercise in a fasted state on plasma low-density lipoprotein cholesterol concentrations in males and females.
    Bradshaw L, Koumanov F, Berry S, Betts JA, et al · · 2023 · cited 1× · PMID 36809567 · DOI 10.1113/ep091005

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Other trials of Meal timing

Trials testing the same drug.

Other recruiting trials for Cardiovascular Diseases

Currently open trials in the same condition.

Other University of Bath trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05279014.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing