Last reviewed · How we verify
NCT05279014
Fasted Exercise and LDL-C
NA trial testing Meal timing in Cardiovascular Diseases in 29 participants. Completed in 30 August 2024.
13 August 2024
Quick facts
| Lead sponsor | University of Bath |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 29 |
| Start date | 30 March 2022 |
| Primary completion | 13 August 2024 |
| Estimated completion | 30 August 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Meal timing
Conditions studied
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
Sponsor
University of Bath
Who can join
Adults 25 to 60, any sex, with Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cardiovascular disease (CVD) is the leading cause of death in the UK and worldwide with low density lipoprotein cholesterol (LDL-C) being one of the most important modifiable risk factors. Physical activity is inexpensive and research shows that it consistently improves high density lipoprotein and triglyceride concentrations. However, fails to improve LDL-C concentrations. Preliminary research suggests fasted exercise could potentially improve LDL-C concentrations. The majority of research in these areas have also mostly been done in males with the results generalised to females. As it is known that lipid metabolism and CVD risk is different between sexes it is possible that the response to fasted exercise may also be different between sexes. This aim of this study is to assess the effect of physical activity performed before or after a meal on plasma LDL-C concentrations in men and women and explore sex differences. The study will also assess the effect of fasted exercise on other CVD risk factors.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The effect of exercise in a fasted state on plasma low-density lipoprotein cholesterol concentrations in males and females.
Bradshaw L, Koumanov F, Berry S, Betts JA, et al · · 2023 · cited 1× · PMID 36809567 · DOI 10.1113/ep091005
Verify or expand the search:
- PubMed search for NCT05279014
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Meal timing
Trials testing the same drug.
- NCT06887543 — The Impact of Time Restricted Eating on Type 2 Diabetes · NA · terminated
- NCT03490825 — Aging Program Project Grant 6 · NA · completed
Other recruiting trials for Cardiovascular Diseases
Currently open trials in the same condition.
- NCT07442578 — Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial · NA · active not recruiting
- NCT07426263 — Effectiveness of a Therapeutic Education Program on Female Sexuality in Women Attending Cardiac Rehabilitation. · NA · active not recruiting
- NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
- NCT07324278 — Hybrid Stroke Rehab With Mirror Priming · NA · recruiting
- NCT07286578 — A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Under · NA · recruiting
Other University of Bath trials
Trials by the same sponsor.
- NCT07360249 — Glucose-fructose Ratio Pilot · NA · recruiting
- NCT06967077 — Exploring the Feasibility and Acceptability of Virtual Reality Exercise for Pain Management, Fear of Movement, Mobility, · NA · not yet recruiting
- NCT07472244 — Does the Development of the Repeated Bout Effect Depend on Oxidative Stress and Inflammation? · NA · recruiting
- NCT07099911 — Neuromuscular Electrical Stimulation and Glucose Control in Spinal Cord Injury · NA · recruiting
- NCT07027553 — Remote Exercise to Improve Physical Activity Levels and Markers of Heart Health in Cystic Fibrosis (RHH-CF) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05279014 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Bath
- Last refreshed: 27 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05279014.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing