NCT05278221 (BIOEPI) is a NA clinical trial of Software EstimLT in Focal Epilepsy, sponsored by Aristotle University Of Thessaloniki.

Who is sponsoring NCT05278221?

NCT05278221 is sponsored by Aristotle University Of Thessaloniki.

What drugs are being tested in NCT05278221?

Interventions in NCT05278221: Software EstimLT.

What condition does NCT05278221 study?

NCT05278221 studies Focal Epilepsy.

Is NCT05278221 still recruiting?

NCT05278221 is currently status unknown. Last updated 10 March 2023.

Last reviewed 2023-03-10 · How we verify

NCT05278221: BIOEPI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

TMS Combined With EEG/EMG as a Biomarker Predicting Antiepileptic Drug Response

Status unknown NA Last updated 10 March 2023

What this trial tests

NA trial testing Software EstimLT in Focal Epilepsy in 42 participants. Status unknown.

Timeline

1 August 2022

Primary endpoint
31 December 2023

31 March 2024

Quick facts

Lead sponsor	Aristotle University Of Thessaloniki
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	42
Start date	1 August 2022
Primary completion	31 December 2023
Estimated completion	31 March 2024
Sites	1 location across Greece

Drugs / interventions tested

Software EstimLT

Conditions studied

Focal Epilepsy — all drugs for Focal Epilepsy →

Sponsor

Aristotle University Of Thessaloniki

Who can join

18 and older, any sex, with Focal Epilepsy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ιn the present study (BIOEPI), the following three hypotheses will be investigated: 1. The proposed TMS-EEG / EMG protocol (which includes software for calculating the cerebral cortex stimulation threshold) in combination with advanced signal analysis and data mining methods will allow the detection of the effect of antiepileptic drugs (AED) with different mechanisms of action (lacosamide \& brivaracetam) in the Central Nervous System under healthy and pathological conditions (Epilepsy). 2. AED-induced changes in selected TMS-EEG / EMG features predict the clinical response of individual epileptic patients to AED. 3. AED-induced changes in selected TMS-EEG / EMG features may predict cognitive side effects.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Focal Epilepsy

Currently open trials in the same condition.

NCT07219407 — A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures · Phase 2 · recruiting
NCT07193277 — Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy · Phase 4 · recruiting
NCT07139457 — Wearable Epileptic Seizure Prediction and Alert Glasses Based on Neuromorphic Computing · NA · active not recruiting
NCT06210022 — Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy · recruiting
NCT05981755 — Breathing Rescue for SUDEP Prevention · NA · recruiting

Other Aristotle University Of Thessaloniki trials

Trials by the same sponsor.

NCT07382479 — NeoAdjuvant ChemoTherapy With KELIM Guided Interval vs. Delayed Interval Debulking Surgery · NA · not yet recruiting
NCT07379905 — MODUCARE Versus Wait-and-See Approach for Histologically Proven Low-grade Cervical Intraepithelial Neoplasia (CIN1) · NA · not yet recruiting
NCT07335016 — The Role of Follicular Flushing at Oocyte Retrieval · NA · not yet recruiting
NCT07297121 — Validation of the Montreal Cognitive Assessment (MoCA) Version 8.x and MoCA-MIS in Greece. · not yet recruiting
NCT07210164 — Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05278221 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Aristotle University Of Thessaloniki
Last refreshed: 10 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05278221.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing