Who is sponsoring NCT05274386?

NCT05274386 is sponsored by Czech Technical University in Prague.

What condition does NCT05274386 study?

NCT05274386 studies Neonatal Respiratory Distress, Very Low Birth Weight Infant.

Is NCT05274386 still recruiting?

NCT05274386 is currently completed. Last updated 25 March 2025.

Last reviewed 2025-03-25 · How we verify

NCT05274386

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Impact of SpO2 Averaging Time on Performance of an Automatic FiO2 Control System: a Randomized Study

Completed NA Last updated 25 March 2025

What this trial tests

NA trial testing Fabian ventilator with PRICO system (Acutronic Medical Systems AG, Hirzel, Switzerland); SpO2 averaging time set to 4to6 s in Neonatal Respiratory Distress in 10 participants. Completed in 30 December 2022.

Timeline

17 February 2022

Primary endpoint
30 December 2022

30 December 2022

Quick facts

Lead sponsor	Czech Technical University in Prague
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	supportive care
Enrollment	10
Start date	17 February 2022
Primary completion	30 December 2022
Estimated completion	30 December 2022
Sites	1 location across Czechia

Drugs / interventions tested

Fabian ventilator with PRICO system (Acutronic Medical Systems AG, Hirzel, Switzerland); SpO2 averaging time set to 4to6 s
Fabian ventilator with PRICO system (Acutronic Medical Systems AG, Hirzel, Switzerland); SpO2 averaging time set to 10 s
Fabian ventilator with PRICO system (Acutronic Medical Systems AG, Hirzel, Switzerland); SpO2 averaging time set to 16 s

Conditions studied

Neonatal Respiratory Distress — all drugs for Neonatal Respiratory Distress →
Very Low Birth Weight Infant — all drugs for Very Low Birth Weight Infant →

Sponsor

Czech Technical University in Prague

Who can join

2 Weeks and older, any sex, with Neonatal Respiratory Distress or Very Low Birth Weight Infant. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to determine the preferred oximeter averaging setting during automated control of FiO2 (A-FiO2) in infants receiving respiratory support and supplemental oxygen.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Evaluation of the impact of oximeter averaging times on automated FiO<sub>2</sub> control in routine NICU care: a randomized cross-over study.
Janota J, Dornakova J, Karadyova V, Brabec R, et al · · 2023 · PMID 37808563 · DOI 10.3389/fped.2023.1240363

Verify or expand the search:

Other recruiting trials for Neonatal Respiratory Distress

Currently open trials in the same condition.

NCT06572033 — Transference of Established Simulated Skills (TEST) Trial · active not recruiting

Other Czech Technical University in Prague trials

Trials by the same sponsor.

NCT06817850 — Neonatal Oximeter Bias Study · not yet recruiting
NCT06626217 — Comparison of Perfusion Index Monitoring Using a Smartwatch and a Pulse Oximeter · NA · not yet recruiting
NCT06635018 — Effect of Pulse Oximeter Device on Measured Perfusion Index Values · NA · completed
NCT06098092 — Long-term Accuracy and Stability of Blood Pressure Measurements From a Smartwatch: Prospective Validation Study · NA · completed
NCT05929196 — Feasibility Evaluation - Blood Glucose Level Monitoring by Microwave Metamaterial Sensor in Blood Samples. · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05274386 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Czech Technical University in Prague
Last refreshed: 25 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05274386.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing