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NCT05274334: D2OBREATH
Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis
NA trial testing Assessment of de novo lipogenesis non-invasively in exhaled breath in De Novo Lipogenesis (DNL) in 5 participants. Completed in 30 September 2022.
30 September 2022
Quick facts
| Lead sponsor | University Children's Hospital Basel |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 5 |
| Start date | 11 May 2022 |
| Primary completion | 30 September 2022 |
| Estimated completion | 30 September 2022 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Assessment of de novo lipogenesis non-invasively in exhaled breath
Conditions studied
- De Novo Lipogenesis (DNL) — all drugs for De Novo Lipogenesis (DNL) →
Sponsor
University Children's Hospital Basel
Who can join
18 and older, any sex, with De Novo Lipogenesis (DNL). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This proof of concept- study is to measure de novo lipogenesis (DNL) non-invasively in exhaled breath in overnight-fasted humans by triggering feeding response by deuterium resolved mass spectrometry.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05274334
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05274334 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Children's Hospital Basel
- Last refreshed: 4 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05274334.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing