Who is sponsoring NCT05273177?

NCT05273177 is sponsored by Istituto Ortopedico Rizzoli.

What drugs are being tested in NCT05273177?

Interventions in NCT05273177: Chronic ankle instability.

What condition does NCT05273177 study?

NCT05273177 studies Chronic Ankle Instability.

Is NCT05273177 still recruiting?

NCT05273177 is currently completed. Last updated 1 March 2023.

Last reviewed 2023-03-01 · How we verify

NCT05273177: KNEE-CAI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Muscle Strength Assessment in Patients With Chronic Ankle Instability

Completed Last updated 1 March 2023

What this trial tests

trial testing Chronic ankle instability in Chronic Ankle Instability in 30 participants. Completed in 28 February 2023.

Timeline

28 February 2022

Primary endpoint
28 January 2023

28 February 2023

Quick facts

Lead sponsor	Istituto Ortopedico Rizzoli
Status	Completed
Study type	OBSERVATIONAL
Enrollment	30
Start date	28 February 2022
Primary completion	28 January 2023
Estimated completion	28 February 2023
Sites	1 location across Italy

Drugs / interventions tested

Chronic ankle instability

Conditions studied

Chronic Ankle Instability — all drugs for Chronic Ankle Instability →

Sponsor

Istituto Ortopedico Rizzoli — full company profile →

Who can join

Adults 18 to 40, any sex, with Chronic Ankle Instability. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with chronic ankle instability (CAI) show biomechanical and neuromuscular alterations during the performance of functional movements not only at the ankle joint level, but also in more proximal joints and segments. Few studies have been conducted to investigate the effects of chronic ankle instability on neuromuscular control at the knee joint level. The aim of this study is to investigate whenther abnormalities exists in maximal and sub-maximal isometric muscle strength expression in patients with CAI.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Individuals With Chronic Ankle Instability Show Abnormalities in Maximal and Submaximal Isometric Strength of the Knee Extensor and Flexor Muscles.
Labanca L, Tedeschi R, Mosca M, Benedetti MG. · · 2024 · cited 16× · PMID 38459686 · DOI 10.1177/03635465241232090

Verify or expand the search:

Other recruiting trials for Chronic Ankle Instability

Currently open trials in the same condition.

NCT07283276 — Effect of Functional Core Stability Training or Cognitive Training on Balance and Postural Control in Chronic Ankle Inst · NA · recruiting
NCT06552533 — Comparison of Resistance Training With and Without Plyometric Exercises on Athletes With Chronic Ankle Instability. · NA · recruiting
NCT06118879 — Role of Sensory Deficits on Sensorimotor Control in Athletes With Chronic Ankle Instability · NA · recruiting

Other Istituto Ortopedico Rizzoli trials

Trials by the same sponsor.

NCT07590882 — Evaluation of Return to Sports Activity After Periacetabular Osteotomy: An Observational Study · enrolling by invitation
NCT07021222 — Multifactorial Strategies for the Prevention of the Risks of Ulceration in Patients Affected by Diabetic Foot (DARE-DiaF · NA · recruiting
NCT07360964 — Clear Cell Chondrosarcoma in Italy · NA · active not recruiting
NCT07140367 — "Transarterial Microembolization (TAME) in Inflammatory Knee Pathology" · recruiting
NCT07102875 — Ready to Sail 2: A Pilot Study of Sail-Assisted Telerehabilitation in Rare Skeletal Diseases · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05273177 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istituto Ortopedico Rizzoli
Last refreshed: 1 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05273177.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing