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NCT05271305: EARLIE
Pilot Study for a National Screening for Familial Hypercholesterolemia
trial in Familial Hypercholesterolemia in 2,000 participants. Status unknown.
30 July 2023
Quick facts
| Lead sponsor | Centre Hospitalier du Luxembourg |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 2,000 |
| Start date | 4 September 2021 |
| Primary completion | 30 July 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across Luxembourg |
Conditions studied
- Familial Hypercholesterolemia — all drugs for Familial Hypercholesterolemia →
Sponsor
Centre Hospitalier du Luxembourg
Who can join
Adults 6 to 13, any sex, with Familial Hypercholesterolemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A pilot study to study the feasibility of the screening of familial hypercholesterolemia within the setting of the legal medical visits at primary school. The pilot study shall evaluate whether this screening set-up is efficient to detect patients having familial hypercholesterolemia, detect further patients by an adjacent cascade screening of family members, to deliver treatment to these patients and to provide this screening in a cost-effective manner.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Screening for familial hypercholesterolaemia in primary school children: protocol for a cross-sectional, feasibility study in Luxembourg city (EARLIE).
Becker M, Adamski A, Fandel F, Vaillant M, et al · · 2022 · cited 3× · PMID 36600332 · DOI 10.1136/bmjopen-2022-066067 -
Facilitating Comprehensive Child Health Monitoring with Real-Time Z-Score assessments using REDCap
Mendon P, Witsch M, Becker M, Adamski A, et al · · 2024 · DOI 10.21203/rs.3.rs-4150703/v1
Verify or expand the search:
- PubMed search for NCT05271305
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Familial Hypercholesterolemia
Currently open trials in the same condition.
- NCT07470723 — The ORIGIN-FH Study · NA · recruiting
- NCT06546137 — National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Un · recruiting
- NCT04529967 — Child-Parent Familial Hypercholesterolemia Screening · recruiting
- NCT06439654 — Atlantic Lipid Lowering Treatment Optimization Program · NA · recruiting
- NCT06458010 — Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH) · EARLY_PHASE1 · recruiting
Other Centre Hospitalier du Luxembourg trials
Trials by the same sponsor.
- NCT03300934 — Adolescence and Diabetes:Can an Automated Closed Loop System Improve Control ? · NA · completed
- NCT03103867 — QUality of Control and slEep in Children With diabeteS, Using New Technology · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05271305 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier du Luxembourg
- Last refreshed: 9 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05271305.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing