Last reviewed · How we verify
NCT05270356: MINDS
MINDS Imaging Ancillary Study
trial testing MRI in Adult Congenital Heart Disease in 195 participants. Completed in 31 May 2025.
31 May 2025
Quick facts
| Lead sponsor | University of Pittsburgh |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 195 |
| Start date | 27 May 2021 |
| Primary completion | 31 May 2025 |
| Estimated completion | 31 May 2025 |
| Sites | 13 locations across Canada, United States |
Drugs / interventions tested
- MRI — full drug profile →
Conditions studied
- Adult Congenital Heart Disease — all drugs for Adult Congenital Heart Disease →
Sponsor
University of Pittsburgh
Who can join
Adults 18 to 30, any sex, with Adult Congenital Heart Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is an ancillary study to the NHLBI-funded Pediatric Heart Network (PHN) "Multi-Institutional Neurocognitive Discovery Study" (MINDS) in Adult Congenital Heart Disease (ACHD). The MINDS-ACHD" study will recruit 500 complex CHD patients between18-30 years old. The investigators propose to quantitate multi-modal neuroimaging biomarkers (brain injury, structure and physiology) which are not only important components of brain and cognitive reserve but can be predictive of neurocognitive decline and early onset of dementia in the aging non-CHD population.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Design and Harmonization Approach for the Multi-Institutional Neurocognitive Discovery Study (MINDS) of Adult Congenital Heart Disease (ACHD) Neuroimaging Ancillary Study: A Technical Note.
Panigrahy A, Schmithorst V, Ceschin R, Lee V, et al · · 2023 · cited 2× · PMID 37754810 · DOI 10.3390/jcdd10090381
Verify or expand the search:
- PubMed search for NCT05270356
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Adult Congenital Heart Disease
Currently open trials in the same condition.
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Other University of Pittsburgh trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05270356 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pittsburgh
- Last refreshed: 31 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05270356.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing