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NCT05269069: RAFAT

Impact of Rheumatoid Arthritis on Body Composition, Bone Marrow Adiposity and Bone Mineral Density: a Case-control Study

Terminated Last updated 16 May 2024
What this trial tests

trial testing Assessment of body composition, bone mineral density and bone marrow adiposity. in Rheumatoid Arthritis in 52 participants. Terminated before completion.

Timeline
17 August 2022
Primary endpoint
2 April 2024
2 April 2024

Quick facts

Lead sponsorUniversity Hospital, Lille
StatusTerminated
Study typeOBSERVATIONAL
Enrollment52
Start date17 August 2022
Primary completion2 April 2024
Estimated completion2 April 2024
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Lille

Who can join

18 and older, any sex, with Rheumatoid Arthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

During rheumatoid arthritis (RA) (in comparison with control subjects), body composition is altered with a loss of lean body mass, bone mass and an accumulation of fat mass. Determination of total body fat and particularly its abdominal distribution (visceral adiposity) is important because of the cardiovascular (excess cardiovascular risk), metabolic (insulin resistance, diabetes and dyslipidemia) and bone (increased fracture risk) risks associated with this endocrine organ. Moreover, we do not have data concerning medullary adiposity in RA. This pilot case-control study will be compare body composition, bone marrow adiposity and bone mineral density in patients with RA versus healthy volunteers.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Rheumatoid Arthritis

Currently open trials in the same condition.

Other University Hospital, Lille trials

Trials by the same sponsor.

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing