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NCT05268952

A Study to Evaluate the Value of Circulating Tumour DNA in Follow-up of Patients With an Advanced Gastroenteropancreatic or Lung Neuroendocrine Tumour Under Everolimus +- SSA Treatment (Liquid-NET 2.0)

Status unknown NA Last updated 7 March 2022
What this trial tests

NA trial testing Liquid biopsies in Neuroendocrine Tumors in 100 participants. Status unknown.

Timeline
27 May 2019
Primary endpoint
27 May 2025
31 December 2025

Quick facts

Lead sponsorUniversity Hospital, Antwerp
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment100
Start date27 May 2019
Primary completion27 May 2025
Estimated completion31 December 2025
Sites3 locations across Belgium, Cyprus

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Antwerp

Who can join

18 and older, any sex, with Neuroendocrine Tumors. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Prospective, multicentric, single arm, POC study to evaluate the value of CtDNA in follow-up of patients treated with everolimus, with or without somatostatin analogues for advanced gastroenteropancreatic or lung neuroendocrine tumours.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Unveiling the Role of Mechanistic Target of Rapamycin Kinase (MTOR) Signaling in Cancer Progression and the Emergence of MTOR Inhibitors as Therapeutic Strategies.
    Mehta D, Rajput K, Jain D, Bajaj A, et al · · 2024 · cited 17× · PMID 39698262 · DOI 10.1021/acsptsci.4c00530
  2. From biology to clinical practice: antiproliferative effects of somatostatin analogs in neuroendocrine neoplasms.
    Melhorn P, Mazal P, Wolff L, Kretschmer-Chott E, et al · · 2024 · cited 3× · PMID 38529270 · DOI 10.1177/17588359241240316

Verify or expand the search:

Other trials of Liquid biopsies

Trials testing the same drug.

Other recruiting trials for Neuroendocrine Tumors

Currently open trials in the same condition.

Other University Hospital, Antwerp trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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