NCT05268250 (R2D2) is a NA clinical trial of R2D2 mHealth intervention in Type 1 Diabetes, sponsored by Nemours Children's Clinic.

Who is sponsoring NCT05268250?

NCT05268250 is sponsored by Nemours Children's Clinic.

What drugs are being tested in NCT05268250?

Interventions in NCT05268250: R2D2 mHealth intervention.

What condition does NCT05268250 study?

NCT05268250 studies Type 1 Diabetes.

Is NCT05268250 still recruiting?

NCT05268250 is currently recruiting now. Last updated 30 October 2025.

Last reviewed 2025-10-30 · How we verify

NCT05268250: R2D2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Remedy to Diabetes Distress (R2D2): A Scalable Screen to Treat Program for School-age Families

Recruiting now NA Last updated 30 October 2025

What this trial tests

NA trial testing R2D2 mHealth intervention in Type 1 Diabetes in 180 participants. Currently enrolling.

Timeline

26 February 2024

Primary endpoint
31 August 2026

31 August 2026

Quick facts

Lead sponsor	Nemours Children's Clinic
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	180
Start date	26 February 2024
Primary completion	31 August 2026
Estimated completion	31 August 2026
Sites	2 locations across United States

Drugs / interventions tested

R2D2 mHealth intervention

Conditions studied

Type 1 Diabetes — all drugs for Type 1 Diabetes →

Sponsor

Nemours Children's Clinic

Who can join

Adults 8 to 65, any sex, with Type 1 Diabetes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This R01 is in response to RFA-DK-19-021, Treating Diabetes Distress to Improve Glycemic Outcomes in Type 1 Diabetes. The objective is to test the feasibility and acceptability of a novel, practical, and potentially scalable screen to treat program for diabetes distress in families of school-age children with T1D (called Remedy to Diabetes Distress \[R2D2\]) and to test the initial efficacy of R2D2 to reduce diabetes distress to improve children's glycemic control.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Early Results of an Innovative Scalable Digital Treatment for Diabetes Distress in Families of School-Age Children with Type 1 Diabetes.
Patton SR, Pierce JS, Kahhan N, Benson M, et al · · 2024 · cited 2× · PMID 39457134 · DOI 10.3390/children11101169

Verify or expand the search:

Other recruiting trials for Type 1 Diabetes

Currently open trials in the same condition.

NCT07061574 — A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New On · Phase 1, PHASE2 · recruiting
NCT07360080 — Long-Term Outcomes of Teplizumab in Routine Clinical Care · recruiting
NCT07457580 — Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs) · recruiting
NCT07212179 — Safety and Feasibility of a Self-Learning Bolus Calculator With Simplified Meal Announcement in Adolescents With Type 1 · NA · recruiting
NCT07287943 — To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes. · NA · recruiting

Other Nemours Children's Clinic trials

Trials by the same sponsor.

NCT06616818 — DASH Diet Intervention for Systemic Hypertension in Adolescents · NA · withdrawn
NCT07218588 — Sanctuary Farm Prescription in Adolescents · NA · recruiting
NCT06406621 — Pilot Trial Assessing the Effectiveness of Laser Hair Depilation on Pilonidal Disease Recurrence in Patients With Darker · NA · recruiting
NCT07154667 — Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction · NA · recruiting
NCT07212049 — Ultrasound Use to Measure Magnetically Controlled Growing Rods · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05268250 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nemours Children's Clinic
Last refreshed: 30 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05268250.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing