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NCT05267366

Chemotherapy Combines With Bevacizumab and PD-1 Inhibitor in Non-squamous NSCLC

Status unknown Phase 2 Last updated 29 March 2023
What this trial tests

Phase 2 trial testing PD-1 inhibitor, Bevacizumab, Carboplatin, Cisplatin, Pemtrexed in PFS in 117 participants. Status unknown.

Timeline
1 February 2022
Primary endpoint
1 February 2024
1 July 2024

Quick facts

Lead sponsorQingdao Central Hospital
PhasePhase 2
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposetreatment
Enrollment117
Start date1 February 2022
Primary completion1 February 2024
Estimated completion1 July 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Qingdao Central Hospital

Who can join

Adults 18 to 80, any sex, with PFS or OS. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In recent years, immunotherapy has emerged as a form of treatment that can lead to robust responses in a subset of patients. PD-1 inhibitor plus chemotherapy showed prolonged survival in NSCLC by the study of KEYNOTE 024, KEYNOTE 189 etc. Thus, this study combines immunotherapeutic agent PD-1 inhibitor with an ant-angiogenic agent, bevacizumab, and double platinum therapy (carboplatin/cisplatin and pemetrexed).

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other Qingdao Central Hospital trials

Trials by the same sponsor.

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Data sources for this page

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