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NCT05267366
Chemotherapy Combines With Bevacizumab and PD-1 Inhibitor in Non-squamous NSCLC
Phase 2 trial testing PD-1 inhibitor, Bevacizumab, Carboplatin, Cisplatin, Pemtrexed in PFS in 117 participants. Status unknown.
1 February 2024
Quick facts
| Lead sponsor | Qingdao Central Hospital |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 117 |
| Start date | 1 February 2022 |
| Primary completion | 1 February 2024 |
| Estimated completion | 1 July 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- PD-1 inhibitor, Bevacizumab, Carboplatin, Cisplatin, Pemtrexed — full drug profile →
Conditions studied
Sponsor
Qingdao Central Hospital
Who can join
Adults 18 to 80, any sex, with PFS or OS. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In recent years, immunotherapy has emerged as a form of treatment that can lead to robust responses in a subset of patients. PD-1 inhibitor plus chemotherapy showed prolonged survival in NSCLC by the study of KEYNOTE 024, KEYNOTE 189 etc. Thus, this study combines immunotherapeutic agent PD-1 inhibitor with an ant-angiogenic agent, bevacizumab, and double platinum therapy (carboplatin/cisplatin and pemetrexed).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05267366
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Qingdao Central Hospital trials
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- NCT06500234 — Nutrition Impact on Immunotherapy of Cancer · Phase 3 · recruiting
- NCT06514118 — Chemoimmunotherapy Plus Residual Lesion Irradiation for the Treatment of Extensive Stage Small-cell Lung Cancer · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05267366 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Qingdao Central Hospital
- Last refreshed: 29 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05267366.
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