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NCT05265793
Camrelizumab Combined With Apatinib in the Treatment of Advanced Sarcomatoid Carcinoma or Carcinosarcoma
Phase 2 trial testing Camrelizumab Combined With Apatinib in PD-1 Immunotherapy in 45 participants. Status unknown.
30 March 2023
Quick facts
| Lead sponsor | Fudan University |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 45 |
| Start date | 21 November 2021 |
| Primary completion | 30 March 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- Camrelizumab Combined With Apatinib — full drug profile →
Conditions studied
- PD-1 Immunotherapy — all drugs for PD-1 Immunotherapy →
- VEGFR-TKI — all drugs for VEGFR-TKI →
- Sarcomatoid Carcinoma — all drugs for Sarcomatoid Carcinoma →
- Carcinosarcoma — all drugs for Carcinosarcoma →
Sponsor
Fudan University
Who can join
Adults 18 to 75, any sex, with PD-1 Immunotherapy or VEGFR-TKI. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is to explore the treatment of advanced sarcomatoid carcinoma or Carcinosarcoma with Carrelizumab combined with Apatinib, in order to provide guidance and experience for new combined therapy in clinic.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Frontiers of Ovarian Carcinosarcoma.
Ismail A, Choi S, Boussios S. · · 2023 · cited 18× · PMID 37938504 · DOI 10.1007/s11864-023-01138-4 -
Molecular Characterizations of Gynecologic Carcinosarcomas: A Focus on the Immune Microenvironment.
Nakad Borrego S, Lengyel E, Kurnit KC. · · 2022 · cited 6× · PMID 36139624 · DOI 10.3390/cancers14184465 -
Sintilimab combined with anlotinib as first-line treatment for advanced sarcomatoid carcinoma of head and neck: a case report and literature review.
Wang L, Huang Y, Sun X. · · 2024 · cited 1× · PMID 38725630 · DOI 10.3389/fonc.2024.1362160 -
Metastatic Sarcomatoid Carcinoma of the Larynx: A Case Report.
Derfoufi J, Rezzoug F, Al Jarroudi O, Brahmi SA, et al · · 2024 · PMID 39463652 · DOI 10.7759/cureus.70331
Verify or expand the search:
- PubMed search for NCT05265793
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05265793 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fudan University
- Last refreshed: 4 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05265793.
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