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NCT05262933
Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
trial testing coffee in Hypotension After Spinal Anesthesia in 2 participants. Completed in 1 July 2022.
1 June 2022
Quick facts
| Lead sponsor | TC Erciyes University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 2 |
| Start date | 15 March 2022 |
| Primary completion | 1 June 2022 |
| Estimated completion | 1 July 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- coffee
- Water (WATER) — full drug profile →
Conditions studied
- Hypotension After Spinal Anesthesia — all drugs for Hypotension After Spinal Anesthesia →
- Post-Dural Puncture Headache — all drugs for Post-Dural Puncture Headache →
Sponsor
TC Erciyes University
Who can join
Adults 18 to 45, female only, with Hypotension After Spinal Anesthesia or Post-Dural Puncture Headache. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating conditions. However spinal anesthesia has some complications as hypotension, bradycardia and Post Dural Puncture Headache (PDPH). A practical strategy for avoiding hypotension during initiation of spinal anesthesia for cesarean delivery includes intravenous crystalloid, in conjunction with administration of vasopressors. PDPH is one of the most frequent complications of spinal anesthesia. Conservative therapies such as bed rest, hydration, and caffeine are commonly used as management. For this study, coffee group of patients will be given unsweetened brewed coffee 150 ml until 2-4 hours before surgery. Patients who accept to drink brewed coffee ( coffee group) and water( control group) will be included in the study. The patient's heart rate, blood pressure, oxygen saturation will be monitored and recorded during operation. Intraoperative will be recorded to amount of vasopressor and intraveous crystalloid. Whether the patient develops PDPH in the postoperative period will be followed for 3 days. In addition abdominal auscultation for bowel sounds hourly and the time of first bowel movements will be recorded. According to the patient's statement, the time of first flatulence and defecation will be followed and recorded.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Does Preoperative Coffee Consumption Prevent Intraoperative Hypotension in Cesarean Section Surgeries?
Talih G, Ulgey A, Şahingöz M, Özdemir F, et al · · 2024 · PMID 39087173 · DOI 10.7759/cureus.63584
Verify or expand the search:
- PubMed search for NCT05262933
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other trials of coffee
Trials testing the same drug.
- NCT07166276 — Association of Coffee With Periodontal Status · completed
- NCT03619304 — Assessment of Anti-cancerous Effect of Green, Roasted and Decaffeinated Coffee on Oral Squamous Cell Carcinoma Cell Line · NA · unknown
- NCT03963180 — Coffee Consumption for Intestinal Function Recovery After Laparoscopic Gynecologic Surgery · NA · completed
- NCT03191877 — Effect of Coffee Consumption on Intestinal Motility · NA · unknown
- NCT03798275 — Coffee Consumption and Pregnancy · NA · completed
Other recruiting trials for Hypotension After Spinal Anesthesia
Currently open trials in the same condition.
- NCT07037654 — Lingual Ondansetron in Reduction of Spinal Hypotension in Cesarean Section · NA · active not recruiting
Other TC Erciyes University trials
Trials by the same sponsor.
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- NCT07529964 — MMP-2/3 and Periapical Healing Outcomes · not yet recruiting
- NCT07526831 — Comparison of the Analgesic Efficacy of Adductor Canal Block and Combined Adductor Canal Block Plus IPACK Block in Knee · recruiting
- NCT07371806 — EFFETCS OF MİNDFULNESS-BASED STRESS REDUCTION İN WOMEN WİTH CORONARY ARTERY DİSEASE · NA · not yet recruiting
- NCT07499947 — Predicting Spinal Hypotension in Cesarean Section · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05262933 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by TC Erciyes University
- Last refreshed: 16 May 2024
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