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NCT05262569
Postoperative Opioid Use and Ileus Occurrence---A Case Control Study
trial testing ileus in Ileus in 596 participants. Completed in 30 June 2022.
31 May 2022
Quick facts
| Lead sponsor | Peking University People's Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 596 |
| Start date | 1 April 2022 |
| Primary completion | 31 May 2022 |
| Estimated completion | 30 June 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- ileus
Conditions studied
- Ileus — all drugs for Ileus →
- Opioid Use — all drugs for Opioid Use →
Sponsor
Peking University People's Hospital
Who can join
18 and older, any sex, with Ileus or Opioid Use. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative ileus (POI) is a significant complication after colorectal surgery, with reported incidence ranging from 10\~30%, leading to increased morbidity, hospital length of stay, and thus medical cost. To determine the risk factors for POI is one of the key elements for Enhanced Recovery after Surgery protocol. Increased perioperative opioid usage has been proposed as an independent risk factor for postoperative ileus, as perioperative opioid minimization has proposed to be an effective measure to decrease the incidence of POI. Although opioids are widely used to attenuate stress during surgery, and represent the cornerstone of pain treatment, anesthesiologists are strive to minimize opioid use to decrease opioid-related GI side effects. In this study, the investigators aim to find out the general occurrence of POI in the laparoscopic colorectal surgery and the effects of the postoperative opioid usage on this outcome. The strategies of opioid minimization was also investigated.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Total postoperative opioid dose is an independent risk factor for prolonged postoperative ileus after laparoscopic colorectal surgery: a case-control study.
Ju H, Shen K, Li J, Feng Y. · · 2024 · cited 5× · PMID 37096402 · DOI 10.4097/kja.22792
Verify or expand the search:
- PubMed search for NCT05262569
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ileus
Currently open trials in the same condition.
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- NCT06815822 — Prevention of Postoperative Hernias in Emergency Surgery · recruiting
Other Peking University People's Hospital trials
Trials by the same sponsor.
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- NCT07294339 — A Randomized Controlled Trial of Acupuncture for the Management of Hot Flashes in Patients With Hormone Receptor-Positiv · NA · not yet recruiting
- NCT07500441 — Digital PCR of CHIP and MR for MRD Monitoring After Allo-HSCT in AML · recruiting
- NCT07487883 — Cadherin 3(CDH3)-Targeted PET in Lung Malignant Tumors · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05262569 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking University People's Hospital
- Last refreshed: 9 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05262569.
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