Last reviewed · How we verify

NCT05262569

Postoperative Opioid Use and Ileus Occurrence---A Case Control Study

Completed Last updated 9 August 2022
What this trial tests

trial testing ileus in Ileus in 596 participants. Completed in 30 June 2022.

Timeline
1 April 2022
Primary endpoint
31 May 2022
30 June 2022

Quick facts

Lead sponsorPeking University People's Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment596
Start date1 April 2022
Primary completion31 May 2022
Estimated completion30 June 2022
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Peking University People's Hospital

Who can join

18 and older, any sex, with Ileus or Opioid Use. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Postoperative ileus (POI) is a significant complication after colorectal surgery, with reported incidence ranging from 10\~30%, leading to increased morbidity, hospital length of stay, and thus medical cost. To determine the risk factors for POI is one of the key elements for Enhanced Recovery after Surgery protocol. Increased perioperative opioid usage has been proposed as an independent risk factor for postoperative ileus, as perioperative opioid minimization has proposed to be an effective measure to decrease the incidence of POI. Although opioids are widely used to attenuate stress during surgery, and represent the cornerstone of pain treatment, anesthesiologists are strive to minimize opioid use to decrease opioid-related GI side effects. In this study, the investigators aim to find out the general occurrence of POI in the laparoscopic colorectal surgery and the effects of the postoperative opioid usage on this outcome. The strategies of opioid minimization was also investigated.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Total postoperative opioid dose is an independent risk factor for prolonged postoperative ileus after laparoscopic colorectal surgery: a case-control study.
    Ju H, Shen K, Li J, Feng Y. · · 2024 · cited 5× · PMID 37096402 · DOI 10.4097/kja.22792

Verify or expand the search:

Other recruiting trials for Ileus

Currently open trials in the same condition.

Other Peking University People's Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05262569.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing