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NCT05262465
Microtransplantation Combined With Azacytidine to Improve the Efficacy of EAML
NA trial testing microtransplantation, HLA-mismatched donor peripheral stem cell infusion in Adult Acute Myeloid Leukemia in 300 participants. Status unknown.
1 July 2023
Quick facts
| Lead sponsor | guomei |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 300 |
| Start date | 1 July 2020 |
| Primary completion | 1 July 2023 |
| Estimated completion | 1 July 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- microtransplantation, HLA-mismatched donor peripheral stem cell infusion — full drug profile →
- Azacitidine (azacitidine) — full drug profile →
- Venetoclax (venetoclax) — full drug profile →
Conditions studied
- Adult Acute Myeloid Leukemia — all drugs for Adult Acute Myeloid Leukemia →
Sponsor
guomei
Who can join
Adults 60 to 85, any sex, with Adult Acute Myeloid Leukemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients enrolled from each center according to confirmed criteria specified in cooperative scheme are recieved induction and consolidation chemotherapy with microtransplantation . Observe the remission rate and 2-year disease-free survival (DFS) and overall survival(OS) rate.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Mitochondria and Acute Leukemia: A Clinician's Perspective.
Iyer P, Jasdanwala SS, Bhatia K, Bhatt S. · · 2024 · cited 6× · PMID 39273651 · DOI 10.3390/ijms25179704
Verify or expand the search:
- PubMed search for NCT05262465
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of microtransplantation, HLA-mismatched donor peripheral stem cell infusion
Trials testing the same drug.
- NCT05095558 — Microtransplantation for Ovarian Cancer · Phase 1, PHASE2 · unknown
- NCT04937842 — Microtransplantation for Advanced and Relapsed Solid Tumors · Phase 1, PHASE2 · unknown
Other recruiting trials for Adult Acute Myeloid Leukemia
Currently open trials in the same condition.
- NCT06329999 — A Prospective, Multicenter, and Exploratory Study of CMGV in the Treatment of Recurrent Adult AML and MDS-EB-2/Elder AML · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05262465 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by guomei
- Last refreshed: 2 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05262465.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing