NCT05260853: PRiVENT

Early Detection and Early Intervention Program in High-risk Patients to Avoid Invasive Long-term Ventilation

Status unknown NA Last updated 2 March 2022

What this trial tests

NA trial testing Weaning Board in Invasive Ventilation in 1,500 participants. Status unknown.

Timeline

1 August 2021

Primary endpoint
30 June 2023

30 April 2024

Quick facts

Lead sponsor	Felix JF Herth
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	1,500
Start date	1 August 2021
Primary completion	30 June 2023
Estimated completion	30 April 2024
Sites	1 location across Germany

Drugs / interventions tested

• Weaning Board

Conditions studied

• Invasive Ventilation — all drugs for Invasive Ventilation →
• Weaning — all drugs for Weaning →

Sponsor

Felix JF Herth

Who can join

30 and older, any sex, with Invasive Ventilation or Weaning. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Early prediction and prevention of prolonged weaning in high risk patients via identification through a computer model and additional assistance in treatment through certified weaning centers in Baden-Württemberg

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

1. Prevention of invasive ventilation (PRiVENT)-a prospective, mixed-methods interventional, multicentre study with a parallel comparison group: study protocol.
   Michels JD, Meis J, Sturm N, Bornitz F, et al · · 2023 · cited 12× · PMID 36998047 · DOI 10.1186/s12913-023-09283-0
2. Risk factors for long-term invasive mechanical ventilation: a longitudinal study using German health claims data.
   Trudzinski FC, Michels-Zetsche JD, Neetz B, Meis J, et al · · 2024 · cited 7× · PMID 38281006 · DOI 10.1186/s12931-024-02693-6
3. E-learning-an interventional element of the PRiVENT project to improve weaning expertise.
   Michels-Zetsche JD, Schubert-Haack J, Tanck K, Neetz B, et al · · 2024 · cited 2× · PMID 38641835 · DOI 10.1186/s12909-024-05416-z
4. Sex-specific differences in risk factors and outcomes for long-term mechanical ventilation: a longitudinal cohort analysis of claims data.
   Trudzinski FC, Neetz B, Dahlhoff J, Höger P, et al · · 2025 · PMID 41062742 · DOI 10.1038/s41598-025-22399-z
5. Prevention of invasive ventilation (PRiVENT) - a prospective, mixed-methods interventional, multicentre study with a parallel comparison group: study protocol
   Michels JD, Meis J, Sturm N, Bornitz F, et al · · 2023 · DOI 10.21203/rs.3.rs-2530478/v1