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NCT05260294
A Comparison Study Between Contrast Spread and Loss of Resistance Techniques
NA trial testing Epidural space identification with cervical epidural steroid injection employing CST and LORT. in Cervical Radiculopathy in 45 participants. Completed in 8 October 2019.
8 October 2019
Quick facts
| Lead sponsor | Yakov Perper, MD |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 45 |
| Start date | 19 August 2019 |
| Primary completion | 8 October 2019 |
| Estimated completion | 8 October 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Epidural space identification with cervical epidural steroid injection employing CST and LORT.
Conditions studied
- Cervical Radiculopathy — all drugs for Cervical Radiculopathy →
- Neck Pain — all drugs for Neck Pain →
- Disc Prolapse With Radiculopathy — all drugs for Disc Prolapse With Radiculopathy →
Sponsor
Yakov Perper, MD
Who can join
18 and older, any sex, with Cervical Radiculopathy or Neck Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Early epidural space identification is critical to the efficacy and safety of cervical epidural steroid injections (CESI) \[1\]. Currently, the accepted method for epidural space recognition is the loss of resistance technique (LORT). I perform CESIs with fluoroscopy only \[2\]. I hypothesized that the contrast spread technique (CST) might recognize epidural space concurrently with or sooner than LORT. I also suggested that smaller needles might be employed with CST but not with LORT. To test my hypotheses, I conducted a comparison study.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Identification of cervical epidural space: A comparison study between contrast spread and loss of resistance techniques.
Perper Y. · · 2022 · cited 2× · PMID 36618582 · DOI 10.3389/fpain.2022.1000209
Verify or expand the search:
- PubMed search for NCT05260294
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cervical Radiculopathy
Currently open trials in the same condition.
- NCT07307846 — Investigation of the Effects of Interlaminar Epidural Steroid Injection on Upper Extremity Proprioception in Patients Wi · NA · recruiting
- NCT07447271 — Ultrasound Guided Cervical Selective Nerve Root Block Versus Fluoroscopic Guided Cervical Transforaminal Epidural Block · NA · active not recruiting
- NCT07319156 — Assessment of Upper Extremity Proprioception in Patients With Cervical Radiculopathy · recruiting
- NCT07207356 — Ultrasound Guided Transcutaneous Pulsed Radiofrequency for Cervical Radiculopathy · NA · recruiting
- NCT07365917 — Effect of Core Stabilization Exercises on Patients With Cervical Radiculopathy · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05260294 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yakov Perper, MD
- Last refreshed: 2 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05260294.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing