NCT05260034

Minimizing Fall-Related Injury in Older Adults: a Motor Learning Approach

Completed NA Last updated 6 November 2024

What this trial tests

NA trial testing FAST Program in Fall Injury in 33 participants. Completed in 5 April 2024.

Timeline

18 July 2022

Primary endpoint
5 April 2024

5 April 2024

Quick facts

Lead sponsor	University of Kansas Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	33
Start date	18 July 2022
Primary completion	5 April 2024
Estimated completion	5 April 2024
Sites	1 location across United States

Drugs / interventions tested

• FAST Program
• Otago Exercise Program

Conditions studied

• Fall Injury — all drugs for Fall Injury →
• Fall Patients — all drugs for Fall Patients →
• Mobility Limitation — all drugs for Mobility Limitation →

Sponsor

University of Kansas Medical Center

Who can join

65 and older, any sex, with Fall Injury or Fall Patients. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Falls are the leading cause of accidental injury and injury-related death among older adults. Despite evidence that falls can be prevented, fall related injuries have not declined over time. Current fall injury prevention techniques targeting mobility and bone strength have merit yet their effectiveness is limited. Indeed, a recent Patient Centered Outcomes Research Institute/National Institute on Aging funded pragmatic trial of individualized multifactorial strategy to prevent serious fall injuries in over 5500 seniors revealed no difference in fall injuries between the intervention and standard care arm. The inconclusive results of the investigation may be due in part to focusing on fall prevention rather than mitigation of fall-related impact acceleration and forces - the "fundamental variables" for injury prevention. A fall-related injury occurs when the body hits the ground with force that is greater than tissue strength. Development of innovative approaches that focus on fundamental variables of injury prevention is needed.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

1. Minimizing fall-related injuries in at-risk older adults: The falling safely training (FAST) study protocol.
   Zanotto T, Chen L, Fang J, Bhattacharya SB, et al · · 2023 · cited 10× · PMID 37122489 · DOI 10.1016/j.conctc.2023.101133
2. Role of the Upper Limb in Limiting Head Impact During Laboratory-Induced Falls in at Fall-Risk Older Adults.
   Chen L, Zanotto T, Fang J, Scharf E, et al · · 2024 · cited 6× · PMID 39501431 · DOI 10.1093/gerona/glae267
3. Strategies to Minimize Fall-related Injuries in Older Adults at Risk of Falls: The Falling Safely Training Study.
   Zanotto T, Chen L, Fang JR, Tabatabaei A, et al · · 2025 · cited 4× · PMID 40243432 · DOI 10.1093/gerona/glaf076
4. Views and experiences of older people taking part in a safe-falling training program: Lessons learned from the FAlling Safely Training (FAST) trial.
   Zanotto A, Zanotto T, Alexander NB, Sosnoff JJ. · · 2024 · cited 3× · PMID 39394576 · DOI 10.1186/s12877-024-05382-7
5. Falling Mechanics Are Altered After Vestibular Schwannoma Surgery-A Case Report.
   D'Silva LJ, Tabatabaei A, Fang J, Chen L, et al · · 2025 · PMID 40534168 · DOI 10.3766/jaaa.240104