Last reviewed · How we verify
NCT05254834
The Vallania Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening
trial testing Freenome Test in Cancer in 7,435 participants. Completed in 12 July 2025.
24 July 2024
Quick facts
| Lead sponsor | Freenome Holdings Inc. |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 7,435 |
| Start date | 15 February 2022 |
| Primary completion | 24 July 2024 |
| Estimated completion | 12 July 2025 |
| Sites | 68 locations across United States |
Drugs / interventions tested
- Freenome Test
Conditions studied
- Cancer — all drugs for Cancer →
Sponsor
Freenome Holdings Inc.
Who can join
30 and older, any sex, with Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This protocol is a case-control, multicenter, diagnostic study to collect blood samples to support the development of blood-based screening tests for multiple cancers.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Shifting the Cancer Screening Paradigm: The Rising Potential of Blood-Based Multi-Cancer Early Detection Tests.
Brito-Rocha T, Constâncio V, Henrique R, Jerónimo C. · · 2023 · cited 72× · PMID 36980276 · DOI 10.3390/cells12060935 -
Transforming cancer screening: the potential of multi-cancer early detection (MCED) technologies.
Imai M, Nakamura Y, Yoshino T. · · 2025 · cited 15× · PMID 39799530 · DOI 10.1007/s10147-025-02694-5 -
Cancer Screening: Present Recommendations, the Development of Multi-Cancer Early Development Tests, and the Prospect of Universal Cancer Screening.
Galeș LN, Păun MA, Anghel RM, Trifănescu OG. · · 2024 · cited 9× · PMID 38539525 · DOI 10.3390/cancers16061191 -
Genomic-Based Early Detection Screening: A Literature Review of Prospective Trials and Emerging Strategies for Gastrointestinal Cancers.
Tizpa E, Sharzehi K, Nabavizadeh N. · · 2024 · PMID 39246640 · DOI 10.7759/cureus.68881
Verify or expand the search:
- PubMed search for NCT05254834
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Freenome Test
Trials testing the same drug.
- NCT05516927 — The Sanderson Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening · completed
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Other Freenome Holdings Inc. trials
Trials by the same sponsor.
- NCT06122077 — Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening · recruiting
- NCT05516927 — The Sanderson Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening · completed
- NCT04369053 — Prevention of Colorectal Cancer Through Multiomics Blood Testing · completed
- NCT03688906 — AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05254834 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Freenome Holdings Inc.
- Last refreshed: 22 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05254834.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing