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Henagliflozin in Patients With Atrial Fibrillation (HENA-AF)

NCT05252624 PHASE3 UNKNOWN

The HENA-AF trial will evaluate the effects of henagliflozin on cardiac structure, function, and biomarkers of HF in patients with AF. Participants with persistent AF, enlarged left atrium, and at least another cardiovascular risk factor will be randomized to henagliflozin or placebo. Cardiac MRI will be performed at baseline and at 6 months to measure the changes in cardiac structure and function. The primary hypothesis is that henagliflozin will reduce the left atrial volume index at 6 months in patients with AF.

Details

Lead sponsorBeijing Anzhen Hospital
PhasePHASE3
StatusUNKNOWN
Enrolment100
Start dateThu Sep 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionSat Sep 30 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

China