Last reviewed · How we verify
NCT05250310: SLYM II
The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease
NA trial testing Chair Yoga in Coronary Artery Disease in 16 participants. Terminated before completion.
24 October 2025
Quick facts
| Lead sponsor | Icahn School of Medicine at Mount Sinai |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 16 |
| Start date | 24 January 2022 |
| Primary completion | 24 October 2025 |
| Estimated completion | 24 October 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Chair Yoga
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
Sponsor
Icahn School of Medicine at Mount Sinai
Who can join
Adults 18 to 80, any sex, with Coronary Artery Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the prospective randomized single center study is to evaluate the effect of a short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease (CVD) risk factors in patients with CVD.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Connecting the Dots: How MicroRNAs Link Asthma and Atherosclerosis.
Zimbru RI, Zimbru EL, Bojin FM, Haidar L, et al · · 2025 · cited 2× · PMID 40332077 · DOI 10.3390/ijms26083570
Verify or expand the search:
- PubMed search for NCT05250310
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Icahn School of Medicine at Mount Sinai trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05250310 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Icahn School of Medicine at Mount Sinai
- Last refreshed: 11 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05250310.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing