Adults 18 to 45, female only, with Post Cesarean Pain. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Comparing the Morphine Milligram Equivalents (MME) Use in the First 24 Hours. Postoperatively After Cesarean SectionPrimary· After cesarean surgery up to 24 hours.
Comparing the morphine milligram equivalents (MME) use in the first 24 hours postoperatively after cesarean section in patients receiving a single dose of 30 mg intravenous ketorolac vs. 60 mg intravenous ketorolac in the operating room after the end of surgery.
Group
Value
95% CI
Ketorolac 30 mg
7.5
0 – 22.5
Ketorolac 60 mg
7.5
0 – 15
Comparing the Morphine Milligram Equivalents (MME) Use During Hospital Stay.Secondary· After cesarean surgery during hospital stay up to 2-3 days.
Comparing the morphine milligram equivalents (MME) use during hospital stay postoperatively after cesarean section in patients receiving a single dose of 30 mg intravenous ketorolac vs. 60 mg intravenous ketorolac in the operating room after the end of surgery.
Group
Value
95% CI
Ketorolac 30 mg
30
7.5 – 54.5
Ketorolac 60 mg
15
0 – 37.5
Comparing Patient Reported Pain Score Assessment.Secondary· After cesarean surgery up to 24 hours.
Comparing patient reported pain score assessment on a scale of 0-10 in the first 24 hours postoperatively after cesarean section in patients receiving a single dose of 30 mg intravenous ketorolac vs. 60 mg intravenous ketorolac in the operating room after the end of surgery. Pain scores postpartum from 0 to 10 based on the Defense and Veterans Pain Rating Scale (DVPRS).
0- No pain
1. Hardly notice pain
2. Notice pain does not interfere with activities
3. Sometimes distracts me
4. Distracts me, can do usual activities
5. Interrupts some activities
6. Hard to ignore, avoid usual activities
7.
Group
Value
95% CI
Ketorolac 30 mg
6
5 – 7
Ketorolac 60 mg
6
5 – 7
Comparing the Time to First Administration of Opioid Pain Medication Postoperatively.Secondary· After cesarean surgery up to 2-3 days.
Comparing the time to first administration of opioid pain medication postoperatively after cesarean section in patients receiving a single dose of 30 mg intravenous ketorolac vs. 60 mg intravenous ketorolac in the operating room after the end of surgery.
Group
Value
95% CI
Ketorolac 30 mg
2.75
2 – 5
Ketorolac 60 mg
15
3 – 25
Pain Score on Discharge HomeSecondary· After cesarean surgery during hospital stay up to 2-3 days.
Comparing the pain score on discharge home in patients receiving a single dose of 30 mg intravenous ketorolac vs. 60 mg intravenous ketorolac in the operating room after the end of surgery.
Pain scores postpartum from 0 to 10 based on the Defense and Veterans Pain Rating Scale (DVPRS).
0- No pain
1. Hardly notice pain
2. Notice pain does not interfere with activities
3. Sometimes distracts me
4. Distracts me, can do usual activities
5. Interrupts some activities
6. Hard to ignore, avoid usual activities
7. Focus of attention, prevents doing daily activities
8. Awful, hard to do anything
9.
Group
Value
95% CI
Ketorolac 30 mg
2
0 – 4
Ketorolac 60 mg
2
0 – 4
Number of Participants With Adverse Maternal Outcomes.Secondary· After cesarean surgery during hospital stay up to 2-3 days.
Evaluating adverse maternal outcomes (acute kidney injury, admission to intensive care unit, maternal death).
Group
Value
95% CI
Ketorolac 30 mg
0
Ketorolac 60 mg
0
Evaluating Type of Skin Incision.Secondary· After cesarean surgery during hospital stay up to 2-3 days.
Evaluating type of skin incision (Pfannenstiel vs. Vertical Midline).
Group
Value
95% CI
Ketorolac 30 mg
45
Ketorolac 60 mg
45
Ketorolac 30 mg
1
Ketorolac 60 mg
1
Sponsor's own description
This is a randomized controlled single blinded trial to compare the morphine milligram equivalents (MME) use in the first 24 hours postoperatively after cesarean section in patients receiving a single dose of 30 mg intravenous ketorolac vs. 60 mg intravenous ketorolac in the operating room after the end of surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ohio State University
Last refreshed: 25 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05248984.