NCT05246839 is a clinical trial of Brief Video in Colorectal Cancer, sponsored by Exact Sciences Corporation.

Who is sponsoring NCT05246839?

NCT05246839 is sponsored by Exact Sciences Corporation.

What drugs are being tested in NCT05246839?

Interventions in NCT05246839: Brief Video, Brief Video Plus.

What condition does NCT05246839 study?

NCT05246839 studies Colorectal Cancer.

Is NCT05246839 still recruiting?

NCT05246839 is currently terminated. Last updated 10 November 2025.

Last reviewed 2025-11-10 · How we verify

NCT05246839

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Informed Choice - Compass

Terminated Last updated 10 November 2025

What this trial tests

trial testing Brief Video in Colorectal Cancer in 1,823 participants. Terminated before completion.

Timeline

28 April 2022

Primary endpoint
31 January 2025

31 January 2025

Quick facts

Lead sponsor	Exact Sciences Corporation
Status	Terminated
Study type	OBSERVATIONAL
Enrollment	1,823
Start date	28 April 2022
Primary completion	31 January 2025
Estimated completion	31 January 2025
Sites	39 locations across United States

Drugs / interventions tested

Brief Video
Brief Video Plus

Conditions studied

Colorectal Cancer — all drugs for Colorectal Cancer →

Sponsor

Exact Sciences Corporation

Who can join

Adults 45 to 70, any sex, with Colorectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of this study is to evaluate the impact of a theoretically grounded video that includes information about CRC screening modality choices on CRC screening rates and time adherent to CRC guidelines. The results will not be posted because the study terminated early and the primary endpoint was not analyzed.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Current Progress in Clinical Research in Secondary Prevention and Early Detection of Colorectal Cancer.
Partyka O, Pajewska M, Czerw A, Deptała A, et al · · 2025 · cited 2× · PMID 39941735 · DOI 10.3390/cancers17030367
The COMPASS study: A prospective, randomized, multi-center trial testing the impact of a clinic-based intervention informing patients of colorectal cancer screening options on screening completion.
Griffin JM, Finney Rutten LJ, Zhu X, Feng Z, et al · · 2022 · PMID 35842109 · DOI 10.1016/j.cct.2022.106852

Verify or expand the search:

Other recruiting trials for Colorectal Cancer

Currently open trials in the same condition.

NCT07152821 — Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcino · Phase 3 · recruiting
NCT07353645 — KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer · Phase 1, PHASE2 · recruiting
NCT07432633 — [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · Phase 1, PHASE2 · recruiting
NCT07523919 — Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes · recruiting
NCT07529301 — Functional and Respiratory Predictors of Early Postoperative Outcomes · recruiting

Other Exact Sciences Corporation trials

Trials by the same sponsor.

NCT05210283 — CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer · active not recruiting
NCT04473625 — Stool Collection Sub-Study of Exact Sciences Protocol 2018-01 · completed
NCT04395391 — Home Usability Study of the SARS-CoV-2 (COVID-19) Test · completed
NCT04213326 — Detecting Cancers Earlier Through Elective Plasma-based CancerSEEK Testing · completed
NCT04144738 — Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C" · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05246839 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Exact Sciences Corporation
Last refreshed: 10 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05246839.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing