Last reviewed · How we verify
NCT05246540: Cervico-TEP et
Evaluation of PET/CT of Cephalic Arteries for the Diagnosis of Giant Cell Arteritis
trial testing Data collection in Giant Cell Arteritis in 70 participants. Completed in 1 December 2021.
1 December 2020
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire Dijon |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 70 |
| Start date | 1 January 2020 |
| Primary completion | 1 December 2020 |
| Estimated completion | 1 December 2021 |
| Sites | 1 location across France |
Drugs / interventions tested
- Data collection — full drug profile →
Conditions studied
- Giant Cell Arteritis — all drugs for Giant Cell Arteritis →
Sponsor
Centre Hospitalier Universitaire Dijon
Who can join
18 and older, any sex, with Giant Cell Arteritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Giant cell arteritis (GCA) is the most common vasculitis in adults. The diagnosis of GCA is evoked by the association of clinical signs and biological anomalies (inflammatory syndrome) in patients over 50 years of age. On the other hand, starting a treatment implies being certain of the diagnosis which requires performing a temporal artery biopsy under local anesthesia. This examination is therefore an invasive procedure for patients whose sensitivity is not optimal. This is why imaging techniques (echo-Doppler or MRI of the temporal arteries) have been developed to look for signs of vasculitis without the need to perform a biopsy. However, these examinations lack sensitivity (=falsely concluding the absence of GCA) and specificity (=falsely concluding the presence of GCA). Recently, advances in imaging, and in particular positron emission tomography (PET), have made it possible to visualize the cephalic arteries, including the temporal artery. The aim of this study is therefore to evaluate the sensitivity and specificity of PET of the cephalic arteries for the diagnosis of GCA and to compare them with those of echo-Doppler and MRI of the temporal arteries.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
PET/CT of cranial arteries for a sensitive diagnosis of giant cell arteritis.
Thibault T, Durand-Bailloud B, Soudry-Faure A, Greigert H, et al · · 2023 · cited 24× · PMID 35866984 · DOI 10.1093/rheumatology/keac430 -
Current developments in the diagnosis and treatment of giant cell arteritis.
Szekeres D, Al Othman B. · · 2022 · cited 5× · PMID 36582285 · DOI 10.3389/fmed.2022.1066503
Verify or expand the search:
- PubMed search for NCT05246540
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Data collection
Trials testing the same drug.
- NCT07010562 — A Multi-site, Pre-clinical, Prospective Data Collection Study in Patients Undergoing a Right Heart Catheterization · not yet recruiting
- NCT07418359 — Comparison of Patient's Physical Activity Levels According to the Physical Activity Level of Their General Practitioner · recruiting
- NCT07197398 — Preoperative Data and the Spinal Spread of Local Anesthetic in Cesarean Section · recruiting
- NCT06998797 — Efficacy of Subcutaneous Infliximab in Acute Severe Ulcerative Colitis: a Multicenter Retrospective Study · not yet recruiting
- NCT07529730 — Outcomes of Surgical Treatment in Patients With Infective Endocarditis · completed
Other recruiting trials for Giant Cell Arteritis
Currently open trials in the same condition.
- NCT07084480 — Giant Cell Arteritis - Ways to Precision Medicine · recruiting
- NCT06894602 — Association of Ultrasonographic Temporal Artery Lesions and Relapse in Patients With Giant Cell Arteritis · recruiting
- NCT05935709 — DANIsh VASculitis Database (DANIVAS) · recruiting
- NCT06460142 — Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic · recruiting
- NCT06011512 — Risk of Diabetes Mellitus in Patients With Giant Cell Arthritis and Polymyalgia Rheumatica. · recruiting
Other Centre Hospitalier Universitaire Dijon trials
Trials by the same sponsor.
- NCT06608004 — Influence of Olfacto-gustatory Sensoriality on the Nutritional Status of Patients With Amyotrophic Lateral Sclerosis · recruiting
- NCT07432789 — Metrological Properties of a Digital Motion Analysis Research Application for Assessing the Motor Abilities and Performa · NA · recruiting
- NCT06776848 — A Pilot, Multicentre, Controlled, Open-label Study Evaluating 24 Months of Lithium Carbonate Treatment in Patients With · Phase 1, PHASE2 · recruiting
- NCT06347302 — Study of Vitreoretinal Molecular Changes During Rhegmatogenous Retinal Detachment · NA · completed
- NCT06252415 — Evaluation of Rapid First-line Genome Sequencing for Prenatal Diagnosis of Congenital Malformations in Comparison With C · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05246540 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire Dijon
- Last refreshed: 29 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05246540.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing