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NCT05242913

Effects of Resistant Potato Starch on the Gut Microbiota

Completed NA Last updated 16 February 2022
What this trial tests

NA trial testing Resistant Potato Starch in Microbiota in 75 participants. Completed in 6 January 2020.

Timeline
30 October 2019
Primary endpoint
6 January 2020
6 January 2020

Quick facts

Lead sponsorMSP Starch Products Inc.
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposebasic science
Enrollment75
Start date30 October 2019
Primary completion6 January 2020
Estimated completion6 January 2020
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

MSP Starch Products Inc.

Who can join

Adults 18 to 69, any sex, with Microbiota. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This was a randomized, double-blind, three-arm, parallel group clinical trial, which assessed the shifts that occur in microbial populations after four weeks of supplementation with resistant potato starch (SolnulTM) at two different dosages, in comparison to a placebo in healthy adults.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Consumption of Solnul<sup>™</sup> Resistant Potato Starch Produces a Prebiotic Effect in a Randomized, Placebo-Controlled Clinical Trial.
    Bush JR, Baisley J, Harding SV, Alfa MJ. · · 2023 · cited 10× · PMID 37049425 · DOI 10.3390/nu15071582
  2. Resistant Potato Starch Supplementation Reduces Serum Free Fatty Acid Levels and Influences Bile Acid Metabolism.
    Bush JR, Iwuamadi I, Han J, Schibli DJ, et al · · 2024 · cited 5× · PMID 39452917 · DOI 10.3390/metabo14100536
  3. Consumption of resistant potato starch produces changes in gut microbiota that correlate with improvements in abnormal bowel symptoms: a secondary analysis of a clinical trial.
    Bush JR, Alfa MJ. · · 2024 · cited 4× · PMID 39605008 · DOI 10.1186/s40795-024-00962-7
  4. Resistant Potato Starch Supplementation Increases the Serum Levels of Choline and Sphingomyelins Without Affecting Trimethylamine Oxide Levels.
    Bush JR, Han J, Goodlett DR. · · 2025 · cited 1× · PMID 41149640 · DOI 10.3390/metabo15100662
  5. Resistant Potato Starch Supplementation Increases Serum Antioxidant Levels in a Randomized Trial.
    Bush JR, Han J, Goodlett DR. · · 2025 · cited 1× · PMID 41149639 · DOI 10.3390/metabo15100661

Verify or expand the search:

Other trials of Resistant Potato Starch

Trials testing the same drug.

Other recruiting trials for Microbiota

Currently open trials in the same condition.

Other MSP Starch Products Inc. trials

Trials by the same sponsor.

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing