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NCT05237635
Defining Decision Thresholds for Judgments on Health Benefits and Harms: Study Protocol
NA trial testing descriptive case-scenarios in Decision Support Techniques in 1,406 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | McMaster University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | triple |
| Primary purpose | other |
| Enrollment | 1,406 |
| Start date | 9 June 2020 |
| Primary completion | 31 December 2022 |
| Estimated completion | 31 December 2022 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- descriptive case-scenarios
Conditions studied
- Decision Support Techniques — all drugs for Decision Support Techniques →
- GRADE Approach — all drugs for GRADE Approach →
Sponsor
McMaster University
Who can join
Adults 18 to 99, any sex, with Decision Support Techniques or GRADE Approach. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this study is an approach to derive and use decision-thresholds for judgments on health benefits and harms using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Defining decision thresholds for judgments on health benefits and harms using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks: a protocol for a randomised methodological study (GRADE-THRESHOLD).
Morgano GP, Mbuagbaw L, Santesso N, Xie F, et al · · 2022 · cited 36× · PMID 35273045 · DOI 10.1136/bmjopen-2021-053246
Verify or expand the search:
- PubMed search for NCT05237635
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05237635 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by McMaster University
- Last refreshed: 14 February 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05237635.
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