NCT05237219 (HEATED) is a NA clinical trial of Passive heating in Diabetes Mellitus, Type 2, sponsored by University of Pecs.

Who is sponsoring NCT05237219?

NCT05237219 is sponsored by University of Pecs.

What drugs are being tested in NCT05237219?

Interventions in NCT05237219: Passive heating, Thermoneutral.

What condition does NCT05237219 study?

NCT05237219 studies Diabetes Mellitus, Type 2, Insulin Resistance.

Is NCT05237219 still recruiting?

NCT05237219 is currently withdrawn. Last updated 20 April 2023.

Last reviewed 2023-04-20 · How we verify

NCT05237219: HEATED

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Heat Therapy in Patients With Type 2 Diabetes Mellitus

Withdrawn NA Last updated 20 April 2023

What this trial tests

NA trial testing Passive heating in Diabetes Mellitus, Type 2. Withdrawn.

Timeline

1 May 2022

Primary endpoint
1 January 2024

1 June 2024

Quick facts

Lead sponsor	University of Pecs
Phase	NA
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Start date	1 May 2022
Primary completion	1 January 2024
Estimated completion	1 June 2024
Sites	1 location across Hungary

Drugs / interventions tested

Passive heating
Thermoneutral

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
Insulin Resistance — all drugs for Insulin Resistance →

Sponsor

University of Pecs

Who can join

Adults 35 to 75, any sex, with Diabetes Mellitus, Type 2 or Insulin Resistance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Type 2 diabetes mellitus (T2DM) is a significant burden worldwide. In addition to lifestyle intervention, heat therapy has been shown to be effective in improving glycemic control. To date, there are no randomized, controlled trials investigating the efficacy of heat therapy in T2DM. Our aim is to investigate whether heat therapy with natural mineral water can improve blood glucose status in T2DM patients. The HEATED study is a two-arm, randomized, controlled study. Patients with T2DM were randomly assigned to Group A (bath in 38 ° C natural thermal mineral water) or Group B (bath in thermoneutral water - 30-32 ° C). Both groups participate in up to five interventions per week, representing 50 to 60 heat therapies over the 12-week study. Each intervention lasts 30 minutes, preceded by a medical examination.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The crucial role and mechanism of insulin resistance in metabolic disease.
Zhao X, An X, Yang C, Sun W, et al · · 2023 · cited 268× · PMID 37056675 · DOI 10.3389/fendo.2023.1149239
Effect of HEAT therapy in patiEnts with type 2 Diabetes mellitus (HEATED): protocol for a randomised controlled trial.
Sebők J, Édel Z, Dembrovszky F, Farkas N, et al · · 2022 · cited 1× · PMID 35820741 · DOI 10.1136/bmjopen-2022-062122

Verify or expand the search:

Other trials of Passive heating

Trials testing the same drug.

NCT05618197 — Chronic Passive Heating in Healthy Older Adults · NA · completed
NCT05622747 — Acute Passive Heating in Healthy Older Adults · NA · completed
NCT04858321 — Chronic Passive Heating in Individuals With T2DM · NA · completed

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other University of Pecs trials

Trials by the same sponsor.

NCT07520877 — Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction · NA · recruiting
NCT05060731 — Iron Supplementation in Upper Non-variceal Gastrointestinal Bleeding · Phase 4 · not yet recruiting
NCT07101510 — V-CPR Under Special Circumstances · NA · completed
NCT07068503 — Study of Running Injuries and Treatment Habits in Romanian Speakers · not yet recruiting
NCT07044219 — The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05237219 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Pecs
Last refreshed: 20 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05237219.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing