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NCT05234528: LATIA

Life After Transient Ischemic Attack

Active, enrolled Last updated 2 May 2024
What this trial tests

trial in Transient Ischemic Attack in 355 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
1 February 2022
Primary endpoint
1 March 2024
1 March 2025

Quick facts

Lead sponsorAalborg University Hospital
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment355
Start date1 February 2022
Primary completion1 March 2024
Estimated completion1 March 2025
Sites1 location across Denmark

Conditions studied

Sponsor

Aalborg University Hospital

Who can join

18 and older, any sex, with Transient Ischemic Attack or Quality of Life. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: Transient ischemic attack (TIA) is defined as acute neurological symptoms of vascular origin, which resolves completely within 24 hours. However, emerging evidence indicates that up to 1/3 of patients is experiencing (non-focal) lasting symptoms, such as fatigue, depression, and anxiety. Aim: The aim of this study is to investigate self-reported lasting symptoms after TIA, timing of these symptoms as well as their potential resolution and characterize patients who have high risk for developing these symptoms. Method: This is a prospective cohort study which will include 350-400 patients with TIA from a single comprehensive stroke care center which serves the population in North Denmark Region, one of five administrative regions in Denmark (Stroke Unit, Aalborg University Hospital). Outcome measures include patient-reported outcomes collected at discharge, 3, 6 and 12 months and semi-structured interviews with a selected sample of patients. Perspective: This study will provide much needed insights into the development of lasting symptoms in patients with TIA in a cohort with presumed high external validity. Based on these results, a person-centered intervention will be designed to support the return to everyday life for patients with TIA.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Long-Term Fatigue Following Transient Ischemic Attack: A Prospective Cohort Study.
    Ebbesen BH, Grøntved S, Hedegaard JN, Johnsen SP, et al · · 2025 · cited 3× · PMID 40367404 · DOI 10.1212/wnl.0000000000213605

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Other recruiting trials for Transient Ischemic Attack

Currently open trials in the same condition.

Other Aalborg University Hospital trials

Trials by the same sponsor.

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Data sources for this page

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