NCT05234216 (COMFORT) is a NA clinical trial of Informed consent in Pain Management, sponsored by Rennes University Hospital.

Who is sponsoring NCT05234216?

NCT05234216 is sponsored by Rennes University Hospital.

What drugs are being tested in NCT05234216?

Interventions in NCT05234216: Informed consent, Surgery, Comfort scale, Pain, Questionnaires.

What condition does NCT05234216 study?

NCT05234216 studies Pain Management, Analgesia.

Is NCT05234216 still recruiting?

NCT05234216 is currently completed. Last updated 23 September 2022.

Last reviewed 2022-09-23 · How we verify

NCT05234216: COMFORT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of a Comfort Scale and a Numerical Pain Scale on Opioid Consumption After Surgery

Completed NA Last updated 23 September 2022

What this trial tests

NA trial testing Informed consent in Pain Management in 885 participants. Completed in 1 July 2022.

Timeline

9 May 2022

Primary endpoint
1 July 2022

1 July 2022

Quick facts

Lead sponsor	Rennes University Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	885
Start date	9 May 2022
Primary completion	1 July 2022
Estimated completion	1 July 2022
Sites	29 locations across France, Lebanon

Drugs / interventions tested

Informed consent
Surgery
Comfort scale
Pain
Questionnaires

Conditions studied

Pain Management — all drugs for Pain Management →
Analgesia — all drugs for Analgesia →

Sponsor

Rennes University Hospital

Who can join

18 and older, any sex, with Pain Management or Analgesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective is to show that the use of therapeutic communication tools, in this case a comfort scale, a low cost and simple to implement method, can reduce pain and therefore the consumption of opioids in the postoperative care unit. Our hypothesis is that the use of a comfort scale will lead to significant postoperative opioid sparing, and consequently to a decrease in the opioid-related side effects The aim of this study is to compare postoperative opioid consumption between patients whose pain is assessed by a numerical verbal scale and those assessed with a comfort scale.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effect of a comfort scale compared with a pain numerical rate scale on opioids consumption in postanaesthesia care unit: the COMFORT study.
Fusco N, Meuret L, Bernard F, Musellec H, et al · · 2024 · cited 2× · PMID 39244480 · DOI 10.1016/j.bja.2024.06.029
Comfort-Focused Assessment and Patient-Reported Experience After Regional versus General Anaesthesia: Post Hoc Analysis of a Cluster-Randomised Trial.
Maurice-Szamburski A, Rozier R, Fusco N, Meuret L, et al · · 2026 · PMID 41177344 · DOI 10.1016/j.accpm.2025.101660

Verify or expand the search:

Other trials of Informed consent

Trials testing the same drug.

NCT04613947 — Effects of Consent Methods Performed According to Intelligence Types on Anxiety Associated with Third Molar Surgery · NA · completed
NCT04433260 — COVID19 and Physical and Emotional Wellbeing of HCP · completed

Other recruiting trials for Pain Management

Currently open trials in the same condition.

NCT07369024 — Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults · Phase 2 · recruiting
NCT07410000 — Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty · NA · recruiting
NCT07467356 — Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip · Phase 3 · recruiting
NCT07454993 — The Effect of Music During Colonoscopy · NA · recruiting
NCT07442539 — The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery · NA · recruiting

Other Rennes University Hospital trials

Trials by the same sponsor.

NCT07527949 — PASTRAMI : Patient-specific Statistics for Microstructure-augmented Connectomics · NA · not yet recruiting
NCT07449832 — Sperm Epigenome in Hodgkin Lymphoma · NA · not yet recruiting
NCT06950398 — Normothermic Oxygenated Perfusion (NMP) Viability Testing Before Transplantation of Discarded Livers · Phase 2 · not yet recruiting
NCT07188753 — Randomized Controlled Trial Testing the Efficacy of Transcranial Magnetic Stimulation by Accelerated & High-dose Theta-b · NA · not yet recruiting
NCT06898099 — Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05234216 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Rennes University Hospital
Last refreshed: 23 September 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05234216.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing