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NCT05230017: CAPSTONE

Chinese AntiphosPholipid Syndrome cohorT cOllaborative NEtworks

Recruiting now Last updated 30 July 2024
What this trial tests

trial in Anti Phospholipid Syndrome in 2,000 participants. Currently enrolling.

Timeline
1 October 2022
Primary endpoint
1 December 2026
1 December 2026

Quick facts

Lead sponsorPeking Union Medical College Hospital
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment2,000
Start date1 October 2022
Primary completion1 December 2026
Estimated completion1 December 2026
Sites18 locations across China

Conditions studied

Sponsor

Peking Union Medical College Hospital

Who can join

Eligibility, any sex, with Anti Phospholipid Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by thrombosis and pregnancy morbidity in patients with persistently positive antiphospholipid antibodies (aPLs). However, large-scale research on general population with persistent aPLs has been lacking. This project proposes to establish the first multicenter cohort of patients with persistently positive aPLs in China and conduct a comprehensive clinical phenotyping study. Based on traditional phenotypes of thrombotic and pregnancy events, the focus will be on extra-standard clinical phenotypes and prospective assessment of event risk and prognosis in aPL-positive population. A prospective analysis of extra-standard antibodies will also be conducted to recommend detection criteria for extra-standard antibody application in China and to assess their clinical significance.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other Peking Union Medical College Hospital trials

Trials by the same sponsor.

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Data sources for this page

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